SCHEMBL7167809

SCHEMBL7167809

O=C(C(C=Cc1ccccc1)=Cc1ccccc1)C(C=Cc1ccccc1)=Cc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.59
LMNA P02545 3/20 0.59
HDAC3 O15379 2/20 0.59
HDAC4 P56524 2/20 0.59
HDAC1 Q13547 2/20 0.59
HDAC2 Q92769 2/20 0.59
HDAC8 Q9BY41 2/20 0.59
HDAC6 Q9UBN7 2/20 0.59
PLIN1 O60240 2/20 0.59
RECQL P46063 2/20 0.59
PLIN5 Q00G26 2/20 0.59
ABHD5 Q8WTS1 2/20 0.59
ALDH1A1 P00352 2/20 0.59
F3 P13726 2/20 0.59
TNKS O95271 1/20 0.59
HCAR2 Q8TDS4 1/20 0.59
HDAC7 Q8WUI4 1/20 0.59
HDAC10 Q969S8 1/20 0.59
HDAC11 Q96DB2 1/20 0.59
TNKS2 Q9H2K2 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2981331 0.88 MAPT (0.59) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL29466710 0.87 MAPT (0.56) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL27680046 0.84 MAPT (0.55) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL28087041 0.84 MAPT (0.55) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL28469635 0.80 ALDH1A1 (0.53) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL28469636 0.80 ALDH1A1 (0.53) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL28461467 0.78 CYP1B1 (0.58) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL10643208 0.77 AKR1C3 (0.47) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL20303734 0.76 MAPT (0.67) MAPTLMNAHDAC3HDAC4HDAC1
SCHEMBL3239009 0.76 MAPT (0.67) MAPTLMNAHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6558740-B1 Printing medium, production process thereof and image-forming process using the medium CANON KABUSHIKI KAISHA (JP) 2003-05-06 US disclosed
EP-0741045-B1 Printing medium, production process thereof and image-forming process using the medium CANON KK (JP) 1999-10-27 EP disclosed
US-5965252-A SUBSTRATE AND INK-RECEIVING LAYER COMPRISING ALUMINA HYDRATE SURFACE TREATED WITH A COUPLING AGENT TO MAKE IT MORE HYDROPHOBIC; FOR WATER BASED INKS; PREVENTS BEADING, PROVIDES IMAGES HIGH IN OPTICAL DENSITY, SURFACE HARDNESS CANON KABUSHIKI KAISHA (JP) 1999-10-12 US disclosed
EP-0741045-A1 Printing medium, production process thereof and image-forming process using the medium CANON KABUSHIKI KAISHA (JP) 1996-11-06 EP disclosed