Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168135 | 1.00 | ALDH1A1 (0.50) | ALDH1A1HCAR2L3MBTL1TDP1KMT2A | |
| SCHEMBL19143851 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HCAR2L3MBTL1TDP1KMT2A | |
| SCHEMBL20006789 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HCAR2L3MBTL1TDP1KMT2A | |
| SCHEMBL22297645 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HCAR2L3MBTL1TDP1KMT2A | |
| SCHEMBL19710611 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HCAR2L3MBTL1TDP1KMT2A | |
| SCHEMBL21697571 | 0.80 | ALDH1A1 (0.46) | ALDH1A1HCAR2L3MBTL1TDP1KMT2A | |
| SCHEMBL19650394 | 0.79 | ALDH1A1 (0.44) | ALDH1A1HCAR2L3MBTL1TDP1KMT2A | |
| SCHEMBL20801933 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HCAR2L3MBTL1TDP1KMT2A | |
| SCHEMBL11687114 | 0.75 | ALDH1A1 (0.57) | ALDH1A1HCAR2L3MBTL1TDP1KMT2A | |
| SCHEMBL23241725 | 0.75 | RCE1 (0.50) | ALDH1A1HCAR2L3MBTL1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6559347-B2 | As dienophiles with dienes such as cyclopentadiene and cyclohexadiene, at an elevated pressure | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2003-05-06 | — | — | US | disclosed |
| US-20020173668-A1 | Diels-alder adducts of epoxybutene and epoxybutene derivatives | WAKE FOREST UNIVERSITY | 2002-11-21 | — | — | US | disclosed |
| US-6380447-B1 | PRESSURIZATION; FORMING BICYCLIC COMPOUNDS | WAKE FOREST UNIVERSITY | 2002-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173668-A1 | Diels-alder adducts of epoxybutene and epoxybutene derivatives | DERA, CYP11B1, SQLE | ALDH1A1 19/4885HCAR2 4227/4885L3MBTL1 1443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.