SCHEMBL7168317

SCHEMBL7168317

Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3(c4ccccc4F)CC3)C(F)(F)F)cc12.Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3(c4ccccc4F)CCC3)C(F)(F)F)cc12

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5641763 0.99 NR3C1 (0.70) NR3C1
SCHEMBL7168839 0.98 NR3C1 (0.69) NR3C1
SCHEMBL5642863 0.98 NR3C1 (0.70) NR3C1
SCHEMBL5643069 0.98 NR3C1 (0.69) NR3C1
SCHEMBL7171583 0.97 NR3C1 (0.69) NR3C1
SCHEMBL5641432 0.97 NR3C1 (0.69) NR3C1
SCHEMBL7173944 0.94 NR3C1 (0.64) NR3C1
SCHEMBL7170326 0.94 NR3C1 (0.65) NR3C1
SCHEMBL7172251 0.93 NR3C1 (0.61) NR3C1
SCHEMBL5642125 0.93 NR3C1 (0.66) NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1309571-A1 NON-STEROIDAL INFLAMMATION INHIBITORS SCHERING AKTIENGESELLSCHAFT (DE) 2003-05-14 EP claimed
WO-2002010143-A1 NON-STEROIDAL INFLAMMATION INHIBITORS SCHERING AKTIENGESELLSCHAFT (DE) 2002-02-07 WO claimed