Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 5/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7171173 | 0.92 | GRIN2D (0.53) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4805406 | 0.81 | GRIN2D (0.47) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4805201 | 0.81 | GRIN2D (0.80) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4809215 | 0.77 | GRIN2B (0.43) | GRIN2BAKR1C3 | |
| SCHEMBL6989168 | 0.73 | DAGLA (0.48) | — | |
| SCHEMBL4888808 | 0.72 | GRIN1 (0.51) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL11995353 | 0.71 | HTR7 (0.50) | AKR1C3 | |
| SCHEMBL2459184 | 0.70 | HTR7 (0.55) | AKR1C3 | |
| SCHEMBL2462975 | 0.70 | HTR7 (0.55) | AKR1C3 | |
| SCHEMBL4813274 | 0.70 | GRIN2D (1.00) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328514-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2003-07-23 | — | — | EP | claimed |
| WO-2002034718-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2002-05-02 | — | — | WO | claimed |
| EP-1328514-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002034718-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2002-05-02 | — | — | WO | disclosed |