SCHEMBL7168607

SCHEMBL7168607

Cc1noc(=O)c2ccc(NC(=O)C(O)(CC(C)(C)c3ccccc3F)C(F)(F)F)cc12.Cc1noc(=O)c2ccc(NC(=O)C(O)(CC(C)(C)c3ccccc3F)C(F)(F)F)cc12

nearest known ligand 0.75

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 20/20 0.75
PGR P06401 5/20 0.75
NR3C2 P08235 4/20 0.75
AR P10275 3/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5642781 1.00 NR3C1 (0.75) NR3C1PGRNR3C2AR
SCHEMBL5642432 0.93 NR3C1 (0.73) NR3C1PGRNR3C2AR
SCHEMBL5641166 0.92 NR3C1 (0.74) NR3C1PGRNR3C2AR
SCHEMBL5643672 0.91 NR3C1 (0.71) NR3C1PGRNR3C2AR
SCHEMBL7172588 0.91 NR3C1 (0.71) NR3C1PGRNR3C2AR
SCHEMBL5644055 0.90 NR3C1 (0.74) NR3C1PGRNR3C2AR
SCHEMBL5642544 0.90 NR3C1 (0.72) NR3C1PGRNR3C2AR
SCHEMBL5643909 0.90 NR3C1 (0.72) NR3C1PGRNR3C2AR
SCHEMBL5642143 0.90 NR3C1 (0.82) NR3C1PGRNR3C2AR
SCHEMBL5643172 0.90 NR3C1 (0.85) NR3C1PGRNR3C2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1309571-A1 NON-STEROIDAL INFLAMMATION INHIBITORS SCHERING AKTIENGESELLSCHAFT (DE) 2003-05-14 EP claimed
WO-2002010143-A1 NON-STEROIDAL INFLAMMATION INHIBITORS SCHERING AKTIENGESELLSCHAFT (DE) 2002-02-07 WO claimed