Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.51 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.51 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.51 |
| ▸ | NDUFA1 | O15239 | 1/20 | 0.51 |
| ▸ | NDUFS4 | O43181 | 1/20 | 0.51 |
| ▸ | NDUFB5 | O43674 | 1/20 | 0.51 |
| ▸ | NDUFB3 | O43676 | 1/20 | 0.51 |
| ▸ | NDUFC1 | O43677 | 1/20 | 0.51 |
| ▸ | NDUFA2 | O43678 | 1/20 | 0.51 |
| ▸ | NDUFS5 | O43920 | 1/20 | 0.51 |
| ▸ | NDUFS7 | O75251 | 1/20 | 0.51 |
| ▸ | NDUFS2 | O75306 | 1/20 | 0.51 |
| ▸ | NDUFS6 | O75380 | 1/20 | 0.51 |
| ▸ | NDUFB1 | O75438 | 1/20 | 0.51 |
| ▸ | NDUFS3 | O75489 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5088775 | 0.99 | TRPV1 (0.62) | TRPV1ALOX15TDP1PPARDKDM4E | |
| SCHEMBL5088772 | 0.99 | TRPV1 (0.62) | TRPV1ALOX15TDP1PPARDKDM4E | |
| SCHEMBL2670106 | 0.88 | TRPV1 (0.59) | TRPV1ALOX15TDP1KDM4ENDUFS8 | |
| SCHEMBL2670101 | 0.88 | TRPV1 (0.59) | TRPV1ALOX15TDP1KDM4ENDUFS8 | |
| SCHEMBL12039195 | 0.88 | TRPV1 (0.58) | TRPV1ALOX15TDP1PPARDKDM4E | |
| SCHEMBL2477691 | 0.88 | TRPV1 (0.58) | TRPV1ALOX15TDP1PPARDKDM4E | |
| SCHEMBL24723567 | 0.87 | TRPV1 (0.60) | TRPV1ALOX15TDP1PPARDKDM4E | |
| SCHEMBL5092438 | 0.87 | TRPV1 (0.60) | TRPV1ALOX15TDP1PPARDKDM4E | |
| SCHEMBL5092441 | 0.87 | TRPV1 (0.60) | TRPV1ALOX15TDP1PPARDKDM4E | |
| SCHEMBL31590280 | 0.86 | PPARD (0.61) | TRPV1PPARDKDM4ENDUFS8COXFA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6566397-B2 | Acyclic isoprenoid ether derivatives as chemotherapeutics | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2003-05-20 | — | — | US | disclosed |
| US-20020045584-A1 | Acyclic isoprenoid ether derivatives as chemotherapeutics | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2002-04-18 | — | — | US | disclosed |