Rac-3-N-Butylphthalide

Rac-3-N-Butylphthalide

SCHEMBL716879

CCCCC1OC(=O)c2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.53
CES2 O00748 1/20 0.52
MAOA P21397 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rac-3-N-Butylphthalide SCHEMBL22551101 1.00 MAOB (0.53) MAOBCES2MAOA
Rac-3-N-Butylphthalide SCHEMBL27598974 1.00 MAOB (0.53) MAOBCES2MAOA
(3S)-Butylphthalide SCHEMBL3756573 1.00 MAOB (0.53) MAOBCES2MAOA
Rac-3-N-Butylphthalide SCHEMBL29744491 0.98 MAOB (0.52) MAOBCES2MAOA
Rac-3-N-Butylphthalide SCHEMBL21381341 0.98 MAOB (0.52) MAOBCES2MAOA
Rac-3-N-Butylphthalide SCHEMBL27742478 0.98 MAOB (0.52) MAOBCES2MAOA
Rac-3-N-Butylphthalide SCHEMBL30233285 0.98 MAOB (0.52) MAOBCES2MAOA
Rac-3-N-Butylphthalide SCHEMBL18011112 0.98 MAOB (0.52) MAOBCES2MAOA
Rac-3-N-Butylphthalide SCHEMBL38661001 0.98 MAOB (0.52) MAOBCES2MAOA
Rac-3-N-Butylphthalide SCHEMBL27997545 0.98 MAOB (0.52) MAOBCES2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3927 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075408-A Butylphthalide cation nanoemulsion and preparation method and application thereof 2026-05-26 CN claimed
WO-2026098615-A1 COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF IN PREPARATION OF DRUGS FOR TREATING CARDIOVASCULAR AND CEREBROVASCULAR DISEASES 上海东西智荟生物医药有限公司 2026-05-15 WO claimed
CN-122036494-A Synthesis method and application of amantadine-butylphthalide eutectic 佛山大学 2026-05-15 CN claimed
EP-4727996-A1 METHOD FOR REMOVAL OF ADDITIVES FROM A POLYMERIC MATERIAL BASF SE (DE) 2026-04-22 EP claimed
EP-4263668-B1 BIO-BASED SULFONE COPOLYMERS FREE OF BPA AND BPS SYENSQO SPECIALTY POLYMERS USA LLC (US) 2026-04-22 EP claimed
US-20260103568-A1 POLYARYLETHERSULFONE COPOLYMER HAVING IMPROVED HYDROPHILICITY SYENSQO SPECIALTYY POLYMRES USA LLC (US) 2026-04-16 US claimed
US-20260085144-A1 GRAFT POLYARYLETHER COPOLYMERS SYENSQO SPECIALTY POLYMERS USA LLC (US) 2026-03-26 US claimed
US-20260085142-A1 GRAFT POLYARYLETHER COPOLYMERS SOLVAY SPECIALTY POLYMERS USA (US) 2026-03-26 US claimed
US-12534571-B2 Amphiphilic block copolymer, preparation method thereof and nanomicelle drug-loading system SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) 2026-01-27 US claimed
US-20250391941-A1 PROCESS FOR THE RECOVERY AND PURIFICATION OF GRAPHITE FROM SPENT BATTERIES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2025-12-25 US claimed
CN-1283621-A Process for preparing optically active 3-n-butyl phenylphthaleine INST OF MEDICINAL MATERIALS CH (CN) 2001-02-14 CN claimed
WO-2001001996-A1 COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING OSTEOPOROSIS UNIVERSITY OF WESTERN AUSTRALIA (AU) 2001-01-11 WO claimed
CN-1257706-A Application of butyl phthalide in preparing medicines curing thrombosis and thrombocyte coagulation INST OF MEDICINAL MATERIALS CH (CN) 2000-06-28 CN claimed
CN-1048158-C Apiolin-A use in preparation of medicine for prevention and treatment of diseases caused by cerebral ischemia PHARMACOLOGY INST CHINESE ACAD (CN) 2000-01-12 CN claimed
EP-0708651-B1 THERAPEUTIC AGENT MAIN CAMP MARKETING PTY LTD (AU) 1999-10-20 EP claimed
EP-0708651-A4 THERAPEUTIC AGENT MAIN CAMP MARKETING PTY LTD (AU) 1998-03-04 EP claimed
CN-1035327-C Synthetic method for rhizoma ligustici internal ester UNIV LANZHOU (CN) 1997-07-02 CN claimed
EP-0708651-A1 THERAPEUTIC AGENT Main Camp Marketing Pty. Ltd. (AU) 1996-05-01 EP claimed
CN-1100097-A Apiolin-A use in preparation of medicine for prevention and treatment of diseases caused by cerebral ischemia PHARMACOLOGY INST CHINESE ACAD (CN) 1995-03-15 CN claimed
WO-1995000157-A1 THERAPEUTIC AGENT MOBIUS CONSULTANCY PTY. LTD. (AU) 1995-01-05 WO claimed