Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Rac-3-N-Butylphthalide SCHEMBL22551101 | 1.00 | MAOB (0.53) | MAOBCES2MAOA | |
| Rac-3-N-Butylphthalide SCHEMBL27598974 | 1.00 | MAOB (0.53) | MAOBCES2MAOA | |
| Rac-3-N-Butylphthalide SCHEMBL716879 | 1.00 | MAOB (0.53) | MAOBCES2MAOA | |
| Rac-3-N-Butylphthalide SCHEMBL29744491 | 0.98 | MAOB (0.52) | MAOBCES2MAOA | |
| Rac-3-N-Butylphthalide SCHEMBL21381341 | 0.98 | MAOB (0.52) | MAOBCES2MAOA | |
| Rac-3-N-Butylphthalide SCHEMBL27742478 | 0.98 | MAOB (0.52) | MAOBCES2MAOA | |
| Rac-3-N-Butylphthalide SCHEMBL30233285 | 0.98 | MAOB (0.52) | MAOBCES2MAOA | |
| Rac-3-N-Butylphthalide SCHEMBL18011112 | 0.98 | MAOB (0.52) | MAOBCES2MAOA | |
| Rac-3-N-Butylphthalide SCHEMBL38661001 | 0.98 | MAOB (0.52) | MAOBCES2MAOA | |
| Rac-3-N-Butylphthalide SCHEMBL27997545 | 0.98 | MAOB (0.52) | MAOBCES2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1136209-C | Process for preparing optically active 3-n-butyl phenylphthaleine | 中国医学科学院药物研究所 | 2004-01-28 | — | — | CN | claimed |
| EP-4674964-A1 | RNA INTERFERENCE STRATEGIES TARGETING SMALL HEAT SHOCK PROTEIN B8 | Universiteit Antwerpen (BE) | 2026-01-07 | — | — | EP | disclosed |
| WO-2025127804-A1 | COMPOSITION FOR PREVENTION, IMPROVEMENT, OR TREATMENT OF POOR OVARIAN RESPONDERS CAUSED BY AGING, COMPRISING BUTYLPHTHALIDE OR ACCEPTABLE SALT THEREOF AS ACTIVE INGREDIENT | 한국 한의학 연구원 | 2025-06-19 | — | — | WO | disclosed |
| CN-118978500-A | Targeted fluorine-containing butylphthalide, synthesis method and application thereof | 苏州摩笛尔科技有限公司 | 2024-11-19 | — | — | CN | disclosed |
| US-11814352-B2 | Salts formed by 2-(1-acyloxy-n-pentyl) benzoic acid and basic amino acid or aminoguanidine, and preparation method and application thereof | JIANGSU KANION PHARMACEUTICAL CO., LTD. (CN) | 2023-11-14 | — | — | US | disclosed |
| US-11814352-B2 | Salts formed by 2-(1-acyloxy-n-pentyl) benzoic acid and basic amino acid or aminoguanidine, and preparation method and application thereof | JIANGSU KANION PHARMACEUTICAL CO., LTD. (CN) | 2023-11-14 | — | — | US | disclosed |
| US-20230248809-A1 | METHODS, DEVICES, AND SYSTEMS FOR TREATING LENS PROTEIN AGGREGATION DISEASES | GLAZIER ALAN NEIL (US) | 2023-08-10 | — | — | US | disclosed |
| WO-2023150617-A2 | METHODS, DEVICES, AND SYSTEMS FOR TREATING LENS PROTEIN AGGREGATION DISEASES | GLAZIER ALAN NEIL (US) | 2023-08-10 | — | — | WO | disclosed |
| CN-108912077-B | Preparation method of chiral phthalide derivative | 中国科学院上海有机化学研究所 | 2022-06-21 | — | — | CN | disclosed |
| US-20220024848-A1 | SALTS FORMED BY 2-(1-ACYLOXY-N-PENTYL) BENZOIC ACID AND BASIC AMINO ACID OR AMINOGUANIDINE, AND PREPARATION METHOD AND APPLICATION THEREOF | JIANGSU KANION PHARMACEUTICAL CO., LTD. (CN) | 2022-01-27 | — | — | US | disclosed |
| US-20070265336-A1 | Application of L-N-Butylphthalide in Preventing and Treating Dementia | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2007-11-15 | — | — | US | disclosed |
| US-20070265336-A1 | Application of L-N-Butylphthalide in Preventing and Treating Dementia | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2007-11-15 | — | — | US | disclosed |
| US-20070112065-A1 | Use of l-butylphthalide in the manufacture of medicaments for prevention and treatment of cerebral infarct | SHIJIAZHUANG PHARMA. GROUP ZHONGQI PHARMACEUTICAL (CN) | 2007-05-17 | — | — | US | disclosed |
| US-20070112065-A1 | Use of l-butylphthalide in the manufacture of medicaments for prevention and treatment of cerebral infarct | SHIJIAZHUANG PHARMA. GROUP ZHONGQI PHARMACEUTICAL (CN) | 2007-05-17 | — | — | US | disclosed |
| US-20070082947-A1 | Use of phthalide derivatives for the treatment and prevention of diabetes mellitus | DSM IP ASSETS B.V. (NL) | 2007-04-12 | — | — | US | disclosed |
| US-20070082947-A1 | Use of phthalide derivatives for the treatment and prevention of diabetes mellitus | DSM IP ASSETS B.V. (NL) | 2007-04-12 | — | — | US | disclosed |
| WO-2006125651-A2 | LIGUSTILIDE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY DISORDERS | DSM IP ASSETS B.V. (NL) | 2006-11-30 | — | — | WO | disclosed |
| CN-1136209-C | Process for preparing optically active 3-n-butyl phenylphthaleine | 中国医学科学院药物研究所 | 2004-01-28 | — | — | CN | disclosed |
| CN-1283621-A | Process for preparing optically active 3-n-butyl phenylphthaleine | INST OF MEDICINAL MATERIALS CH (CN) | 2001-02-14 | — | — | CN | disclosed |
| CN-1257706-A | Application of butyl phthalide in preparing medicines curing thrombosis and thrombocyte coagulation | INST OF MEDICINAL MATERIALS CH (CN) | 2000-06-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814352-B2 | Salts formed by 2-(1-acyloxy-n-pentyl) benzoic acid and basic amino acid or aminoguanidine, and preparation method and application thereof | KCNB1, KCNMB1, KCNAB1 | MAOB 365/4885CES2 3160/4885MAOA 3034/4885 |
| US-20070265336-A1 | Application of L-N-Butylphthalide in Preventing and Treating Dementia | PSEN1, PSEN2, BCHE | MAOB 179/4885CES2 1472/4885MAOA 200/4885 |
| US-20070082947-A1 | Use of phthalide derivatives for the treatment and prevention of diabetes mellitus | IAPP, SLC5A2, SLC2A4 | MAOB 3399/4885CES2 3549/4885MAOA 3344/4885 |
| US-20070112065-A1 | Use of l-butylphthalide in the manufacture of medicaments for prevention and treatment of cerebral infarct | GABARAPL1, GABARAPL2, NLN | MAOB 328/4885CES2 1536/4885MAOA 378/4885 |
| US-20220024848-A1 | SALTS FORMED BY 2-(1-ACYLOXY-N-PENTYL) BENZOIC ACID AND BASIC AMINO ACID OR AMINOGUANIDINE, AND PREPARATION METHOD AND APPLICATION THEREOF | KCNB1, KCNMB1, KCNAB1 | MAOB 365/4885CES2 3160/4885MAOA 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.