Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 6/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3804525 | 0.80 | POLB (0.49) | POLBHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL29281939 | 0.80 | HDAC3 (0.50) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL10538923 | 0.76 | HDAC3 (0.50) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL6685035 | 0.76 | L3MBTL1 (0.48) | POLBADRA1ASLC6A3L3MBTL1MEN1 | |
| SCHEMBL27782631 | 0.76 | POLB (0.45) | POLBHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL28351862 | 0.76 | POLB (0.53) | POLBHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL4557607 | 0.75 | L3MBTL1 (0.48) | POLBHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL11846515 | 0.74 | POLB (0.44) | POLBHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL9545400 | 0.74 | POLB (0.44) | POLBHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL11047843 | 0.74 | L3MBTL1 (0.47) | POLBADRA1ASLC6A3L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534489-B1 | Organophosphorus compounds and the use thereof | JOMAA PHARMAKA GMBH (DE) | 2003-03-18 | — | — | US | disclosed |
| EP-1133500-B1 | ORGANOPHOSPHOROUS COMPOUNDS AND THE USE THEREOF | JOMAA PHARMAKA GMBH (DE) | 2002-09-11 | — | — | EP | disclosed |
| EP-1133500-A1 | ORGANOPHOSPHOROUS COMPOUNDS AND THE USE THEREOF | Jomaa Pharmaka GmbH (DE) | 2001-09-19 | — | — | EP | disclosed |
| WO-2000031085-A1 | ORGANOPHOSPHOROUS COMPOUNDS AND THE USE THEREOF | JOMAA PHARMAKA GMBH (DE) | 2000-06-02 | — | — | WO | disclosed |