Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 3/20 | 0.40 |
| ▸ | FNTB | P49356 | 3/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644048 | 0.81 | FNTA (0.52) | FNTAFNTBPGGT1B | |
| SCHEMBL5659774 | 0.76 | FNTA (0.52) | FNTAFNTBPGGT1BMEN1CYP1A2 | |
| SCHEMBL7092843 | 0.76 | FNTA (0.53) | FNTAFNTBPGGT1B | |
| SCHEMBL2177983 | 0.72 | FNTA (0.54) | FNTAFNTBPGGT1B | |
| SCHEMBL5656175 | 0.71 | FNTA (0.56) | FNTAFNTBPGGT1BMEN1CYP1A2 | |
| SCHEMBL3979831 | 0.70 | FNTA (0.38) | FNTAFNTBPGGT1B | |
| SCHEMBL5657377 | 0.70 | FNTA (0.57) | FNTAFNTBPGGT1BMEN1CYP1A2 | |
| SCHEMBL5656453 | 0.70 | FNTA (0.59) | FNTAFNTBPGGT1BMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL5656686 | 0.69 | FNTA (0.56) | FNTAFNTBPGGT1BMEN1CYP1A2 | |
| SCHEMBL7091902 | 0.69 | FNTA (0.54) | FNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322636-A1 | FARNESYL TRANSFERASE INHIBITING 6- (SUBSTITUTED PHENYL)METHYL]-QUINOLINE AND QUINAZOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024683-A1 | FARNESYL TRANSFERASE INHIBITING 6-[(SUBSTITUTED PHENYL)METHYL]-QUINOLINE AND QUINAZOLINE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 2002-03-28 | — | — | WO | disclosed |