Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126798 | 0.88 | GAA (0.65) | GAAHPGDLMNAMAPK1CYP1A2 | |
| SCHEMBL29530425 | 0.88 | GAA (0.65) | GAAHPGDLMNAMAPK1CYP1A2 | |
| SCHEMBL7169592 | 0.86 | HPGD (0.53) | HPGDLMNAMAPK1CYP1A2PGR | |
| SCHEMBL7173457 | 0.86 | HPGD (0.53) | HPGDLMNAMAPK1CYP1A2PGR | |
| SCHEMBL10621312 | 0.86 | GAA (0.59) | GAAHPGDLMNAMAPK1CYP1A2 | |
| SCHEMBL7175178 | 0.84 | HPGD (0.47) | GAAHPGDLMNAMAPK1CYP1A2 | |
| Fumaric Acid SCHEMBL8443223 | 0.82 | GAA (0.57) | GAAHPGDLMNAMAPK1CYP1A2 | |
| Maleic Acid SCHEMBL8441601 | 0.82 | GAA (0.57) | GAAHPGDLMNAMAPK1CYP1A2 | |
| SCHEMBL7172916 | 0.82 | HPGD (0.48) | GAAHPGDLMNAMAPK1CYP1A2 | |
| SCHEMBL7098970 | 0.82 | HPGD (0.62) | GAAHPGDLMNAMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586519-B1 | Compounds which exhibit enhanced ultraviolet radiation absorption | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | claimed |
| US-6576797-B1 | Thioether substituted hydroxybenzophenones and stabilized compositions | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-10 | — | — | US | claimed |
| US-6586519-B1 | Compounds which exhibit enhanced ultraviolet radiation absorption | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | disclosed |
| US-6576797-B1 | Thioether substituted hydroxybenzophenones and stabilized compositions | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-10 | — | — | US | disclosed |
| EP-0675108-B1 | Thioether substituted hydroxybenzophenones and stabilized compositions | CIBA GEIGY AG (CH) | 1998-06-10 | — | — | EP | disclosed |
| EP-0675108-A1 | Thioether substituted hydroxybenzophenones and stabilized compositions | CIBA-GEIGY AG (CH) | 1995-10-04 | — | — | EP | disclosed |