Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA4 | P54764 | 1/20 | 0.43 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HEXA | P06865 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20837070 | 0.72 | MAPK1 (0.43) | HPGDNFKB1RAB9ANFKB2RELA | |
| SCHEMBL10960154 | 0.71 | HRH2 (0.34) | FFAR2ALDH1A1 | |
| SCHEMBL7307418 | 0.70 | HRH2 (0.37) | FFAR2NPY5RALDH1A1 | |
| SCHEMBL21315881 | 0.69 | HEXA (0.43) | EPHA4PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL1856310 | 0.65 | EPHA4 (0.51) | EPHA4FFAR2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL19941737 | 0.64 | PDE5A (0.36) | FFAR2ALDH1A1 | |
| SCHEMBL19941723 | 0.64 | PDE5A (0.36) | FFAR2ALDH1A1 | |
| SCHEMBL8902605 | 0.64 | GABRA1 (0.39) | S1PR1S1PR5TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL15020704 | 0.64 | IKBKB (0.45) | MAPTSMN1; SMN2NPSR1NOTUM | |
| SCHEMBL5184422 | 0.63 | BRD4 (0.34) | USP2MAPTALOX15SMN1; SMN2GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004050650-A1 | ANILINOPYRAZOLE DERIVATIVES USEFUL FOR THE TREATMENT OF DIABETES | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-06-17 | — | — | WO | disclosed |