Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841280 | 0.87 | THRB (0.56) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL29413361 | 0.87 | THRB (0.56) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL14173222 | 0.82 | THRB (0.51) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL30007447 | 0.82 | THRB (0.51) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL10871851 | 0.82 | THRB (0.51) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL27594054 | 0.81 | THRB (0.48) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL29497650 | 0.80 | THRB (0.50) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL218920 | 0.80 | THRB (0.50) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL135370 | 0.78 | THRB (0.49) | THRBTHRAKDM4EMAPTHPGD | |
| SCHEMBL5887392 | 0.78 | MAPT (0.56) | THRBTHRAKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1279720-A1 | FLAME RETARDANT, FLAME-RETARDANT RESIN COMPOSITION, MOLDED OBJECT, AND ELECTRONIC PART | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2003-01-29 | — | — | EP | disclosed |
| US-4710549-A | Cross-linked phosphazene polymer | ETHYL CORPORATION (US) | 1987-12-01 | — | — | US | disclosed |