Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6989074 | 0.92 | KMT2A (0.35) | ALDH1A1ACEKMT2ACYP2C9CYP3A4 | |
| SCHEMBL6697354 | 0.91 | SYK (0.41) | CPB1ALDH1A1CYP1A2MEN1LMNA | |
| SCHEMBL7026783 | 0.90 | ACE (0.37) | ALDH1A1ACEMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7162370 | 0.87 | CPB1 (0.42) | CPB1ALDH1A1GAACYP1A2DPP4 | |
| SCHEMBL7092695 | 0.87 | CPB1 (0.42) | CPB1ALDH1A1GAACYP1A2DPP4 | |
| SCHEMBL7099096 | 0.86 | CPB1 (0.44) | CPB1ALDH1A1GAACYP1A2DPP4 | |
| SCHEMBL7021089 | 0.86 | CPB1 (0.44) | CPB1ALDH1A1GAACYP1A2DPP4 | |
| SCHEMBL6986343 | 0.86 | CPB1 (0.44) | CPB1ALDH1A1GAACYP1A2DPP4 | |
| SCHEMBL6696742 | 0.83 | KMT2A (0.42) | ALDH1A1ACEKMT2ACTSLCYP2C9 | |
| SCHEMBL6704197 | 0.82 | KMT2A (0.42) | CPB1KMT2ACTSKCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358154-A2 | PYRROLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF NEURAMINIDASES | Abbott Laboratories (US) | 2003-11-05 | — | — | EP | disclosed |
| WO-2001028996-A2 | PYRROLIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF NEURAMINIDASES | ABBOTT LABORATORIES (US) | 2001-04-26 | — | — | WO | disclosed |