Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 7/20 | 0.54 |
| ▸ | CTSB | P07858 | 4/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7170752 | 1.00 | CAPN1 (0.54) | CAPN1CTSBACECTSL | |
| SCHEMBL2911854 | 0.85 | CAPN1 (0.58) | CAPN1CTSBACE | |
| SCHEMBL14663480 | 0.82 | CAPN1 (0.59) | CAPN1CTSBACECTSL | |
| SCHEMBL14663479 | 0.82 | CAPN1 (0.59) | CAPN1CTSBACECTSL | |
| SCHEMBL2369340 | 0.81 | CAPN1 (0.61) | CAPN1CTSBACE | |
| SCHEMBL3292711 | 0.81 | CAPN1 (0.61) | CAPN1CTSBACE | |
| SCHEMBL17865652 | 0.81 | CAPN1 (0.61) | CAPN1CTSBACE | |
| SCHEMBL16485210 | 0.79 | CTSC (0.57) | CAPN1CTSBACE | |
| SCHEMBL10045690 | 0.78 | CAPN1 (0.58) | CAPN1CTSBACE | |
| SCHEMBL2269431 | 0.78 | CAPN1 (0.58) | CAPN1CTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576613-B1 | Arginine derivatives; monitoring plasminogen activator levels; inhibiting angiogenesis and tumor cell growth | CORVAS INTERNATIONAL, INC. | 2003-06-10 | — | — | US | disclosed |
| US-6432922-B1 | ANTITUMOR AGENTS; ANGIOGENESIS INHIBITORS | CORVAS INTERNATIONAL, INC. | 2002-08-13 | — | — | US | disclosed |