⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508170 | 0.84 | — | — | |
| SCHEMBL8470317 | 0.84 | — | — | |
| SCHEMBL15097098 | 0.81 | — | — | |
| SCHEMBL12695378 | 0.78 | — | — | |
| SCHEMBL11745733 | 0.75 | — | — | |
| SCHEMBL9966839 | 0.75 | — | — | |
| SCHEMBL12112586 | 0.75 | — | — | |
| SCHEMBL7253267 | 0.73 | MAOA (0.32) | — | |
| SCHEMBL4420707 | 0.72 | — | — | |
| SCHEMBL12695299 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6545183-B1 | Alkylation in presence of strong base; cyclization | CHIROTECH TECHNOLOGY LIMITED (GB) | 2003-04-08 | — | — | US | disclosed |
| EP-1028967-B1 | PROCESS FOR PREPARING CYCLIC PHOSPHINES | CHIROTECH TECHNOLOGY LTD (GB) | 2001-09-26 | — | — | EP | disclosed |
| EP-1028967-A1 | PROCESS FOR PREPARING CYCLIC PHOSPHINES | Chirotech Technology Limited (GB) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999024444-A1 | PROCESS FOR PREPARING CYCLIC PHOSPHINES | CHIROTECH TECHNOLOGY LIMITED (GB) | 1999-05-20 | — | — | WO | disclosed |