Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31753460 | 1.00 | LMNA (0.49) | LMNAHTTSMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL11032631 | 0.86 | LMNA (0.43) | LMNAHTTSMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL5762355 | 0.83 | LMNA (0.51) | LMNAHTTSMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL2164246 | 0.83 | HDAC8 (0.39) | LMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL8398139 | 0.82 | SMN1; SMN2 (0.38) | LMNAHTTSMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL30099886 | 0.81 | LMNA (0.49) | LMNAHTTSMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL4258915 | 0.81 | HTT (0.49) | LMNAHTTSMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL103421 | 0.81 | LMNA (0.49) | LMNAHTTSMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL18577930 | 0.81 | LMNA (0.49) | LMNAHTTSMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL11110064 | 0.79 | LMNA (0.40) | LMNAHTTSMN1; SMN2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115939519-A | Electrolyte and battery containing same | 蜂巢能源科技(无锡)有限公司 | 2023-04-07 | — | — | CN | claimed |
| US-11590260-B2 | Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system | EDWARDS LIFESCIENCES CORPORATION (US) | 2023-02-28 | — | — | US | claimed |
| US-20190216978-A1 | METHODS FOR TREATING BIOPROSTHETIC TISSUE USING A NUCLEOPHILE/ELECTROPHILE IN A CATALYTIC SYSTEM | EDWARDS LIFESCIENCES CORPORATION | 2019-07-18 | — | — | US | claimed |
| US-10238771-B2 | Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system | EDWARDS LIFESCIENCES CORPORATION (US) | 2019-03-26 | — | — | US | claimed |
| EP-2916882-A1 | METHODS FOR TREATING BIOPROSTHETIC TISSUE USING A NUCLEOPHILE/ELECTROPHILE IN A CATALYTIC SYSTEM | Edwards Lifesciences Corporation (US) | 2015-09-16 | — | — | EP | claimed |
| WO-2014074870-A1 | METHODS FOR TREATING BIOPROSTHETIC TISSUE USING A NUCLEOPHILE/ELECTROPHILE IN A CATALYTIC SYSTEM | EDWARDS LIFESCIENCES CORPORATION (US) | 2014-05-15 | — | — | WO | claimed |
| US-20140127804-A1 | METHODS FOR TREATING BIOPROSTHETIC TISSUE USING A NUCLEOPHILE/ELECTROPHILE IN A CATALYTIC SYSTEM | EDWARDS LIFESCIENCES CORPORATION (US) | 2014-05-08 | — | — | US | claimed |
| EP-0397474-A2 | Photosensitive composition | KABUSHIKI KAISHA TOSHIBA (JP) | 1990-11-14 | — | — | EP | claimed |
| JP-59110682-A | — | — | None | — | — | JP | disclosed |
| JP-59219279-A | — | — | None | — | — | JP | disclosed |
| JP-59204175-A | — | — | None | — | — | JP | disclosed |
| JP-59067275-A | — | — | None | — | — | JP | disclosed |
| JP-63096184-A | — | — | None | — | — | JP | disclosed |
| US-12600917-B2 | Lubricating oil additive composition and lubricating oil composition | ENEOS CORPORATION (JP) | 2026-04-14 | — | — | US | disclosed |
| JP-S59110682-A | 5-FLUOROURACIL DERIVATIVE AND ITS PREPARATION | TERUMO CORP | 1984-06-26 | — | — | JP | disclosed |
| EP-0108645-A2 | Novel ailanthone derivative | SUNTORY LIMITED (JP) | 1984-05-16 | — | — | EP | disclosed |
| JP-S5967275-A | 5-FLUOROURACIL DERIVATIVE AND ITS PREPARATION | TERUMO CORP | 1984-04-16 | — | — | JP | disclosed |
| US-4301231-A | SOLUBLE FILM FORMING POLYMER CONTAINING VINYL SILYL BRANCHES | TORAY INDUSTRIES, INCORPORATED (JP) | 1981-11-17 | — | — | US | disclosed |
| US-4206310-A | Process for the preparation of esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-06-03 | — | — | US | disclosed |
| JP-S06396184-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12600917-B2 | Lubricating oil additive composition and lubricating oil composition | PHOSPHO1, F12, C9 | LMNA 1926/4885HTT 3206/4885SMN1; SMN2 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.