Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7176527 | 0.97 | KDM4E (0.57) | KDM4EHSD17B10L3MBTL1ATMHPGD | |
| Hydrochloric Acid SCHEMBL7175594 | 0.97 | KDM4E (0.57) | KDM4EHSD17B10L3MBTL1ATMHPGD | |
| Hydrochloric Acid SCHEMBL7172131 | 0.97 | KDM4E (0.57) | KDM4EHSD17B10L3MBTL1ATMHPGD | |
| Hydrochloric Acid SCHEMBL7181171 | 0.97 | KDM4E (0.57) | KDM4EHSD17B10L3MBTL1ATMHPGD | |
| Hydrochloric Acid SCHEMBL7181379 | 0.97 | KDM4E (0.57) | KDM4EHSD17B10L3MBTL1ATMHPGD | |
| Hydrochloric Acid SCHEMBL7174794 | 0.97 | KDM4E (0.57) | KDM4EHSD17B10L3MBTL1ATMHPGD | |
| Hydrochloric Acid SCHEMBL7171611 | 0.93 | KDM4E (0.55) | KDM4EHSD17B10L3MBTL1ATMHPGD | |
| Hydrochloric Acid SCHEMBL7183851 | 0.91 | KDM4E (0.70) | KDM4EHSD17B10L3MBTL1ATMHPGD | |
| Hydrochloric Acid SCHEMBL7175966 | 0.90 | KDM4E (0.53) | KDM4EHSD17B10L3MBTL1ATMHPGD | |
| Hydrochloric Acid SCHEMBL7176681 | 0.90 | KDM4E (0.55) | KDM4EHSD17B10L3MBTL1ATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |