SCHEMBL717287

SCHEMBL717287

Nc1nc2c(c(=O)[nH]1)N[C@H](CNc1ccc(C(=O)NC(CC(C=O)C(=O)O)C(=O)O)cc1)CN2

nearest known ligand 0.76

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SOST Q9BQB4 1/20 0.76
▸ FPGS Q05932 2/20 0.75
▸ GART P22102 6/20 0.57
▸ DHFR P00374 1/20 0.55
▸ ATIC P31939 3/20 0.49
▸ LMNA P02545 1/20 0.48
▸ MTHFD1 P11586 2/20 0.48
▸ NOS3 P29474 1/20 0.46
▸ NOS1 P29475 1/20 0.46
▸ NOS2 P35228 1/20 0.46
▸ MTHFD2 P13995 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223673 1.00 SOST (0.76) SOSTFPGSGARTDHFRATIC
SCHEMBL714907 1.00 SOST (0.76) SOSTFPGSGARTDHFRATIC
SCHEMBL28327411 0.99 SOST (0.75) SOSTFPGSGARTDHFRATIC
SCHEMBL27325154 0.99 SOST (0.75) SOSTFPGSGARTDHFRATIC
SCHEMBL28088376 0.99 SOST (0.75) SOSTFPGSGARTDHFRATIC
Formic Acid SCHEMBL4636836 0.98 SOST (0.74) SOSTFPGSGARTDHFRATIC
Pyrimidine SCHEMBL27528328 0.96 SOST (0.71) SOSTFPGSGARTDHFRATIC
Tetrahydrofolate SCHEMBL27310590 0.95 SOST (0.86) SOSTFPGSGARTDHFRATIC
Tetrahydrofolate SCHEMBL27730864 0.94 SOST (0.84) SOSTFPGSGARTDHFRATIC
SCHEMBL5969477 0.93 SOST (0.75) SOSTFPGSGARTDHFRATIC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8524269-B2 Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions PBM PHARMACEUTICALS, INC. (US) 2013-09-03 — — US claimed
US-8173160-B2 Improving bioabsorption, gastric acid degradation resistance; B vitamins, omega-3 fatty acids PBM PHARMACEUTICALS, INC. (US) 2012-05-08 — — US claimed
US-20120052128-A1 ORAL COMPOSITIONS COMPRISING EDIBLE OILS AND VITAMINS AND/OR MINERALS AND METHODS FOR MAKING ORAL COMPOSITIONS PBM PHARMACEUTICALS, INC. (US) 2012-03-01 — — US claimed
US-8075910-B2 Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions PBM PHARMACEUTICALS, INC. (US) 2011-12-13 — — US claimed
US-20080274175-A1 Compositions Comprising Edible Oils and Vitamins and/or Minerals and Methods for Making the Compositions PBM PHARMACEUTICALS, INC. 2008-11-06 — — US claimed
EP-1765089-A2 COMPOSITIONS COMPRISING EDIBLE OILS AND VITAMINS AND/OR MINERALS AND METHODS FOR MAKING THE COMPOSITIONS PBM Pharmaceuticals, Inc. (US) 2007-03-28 — — EP claimed
US-20060188607-A1 Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions PBM PHARMACEUTICALS, INC. 2006-08-24 — — US claimed
WO-2005112654-A2 COMPOSITIONS COMPRISING EDIBLE OILS AND VITAMINS AND/OR MINERALS AND METHODS FOR MAKING THE COMPOSITIONS PBM PHARMACEUTICALS, INC. (US) 2005-12-01 — — WO claimed
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