Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.93 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7171435 | 0.96 | KDM4E (0.93) | KDM4EHRH3ALDH1A1HTTATM | |
| Hydrochloric Acid SCHEMBL7175648 | 0.96 | KDM4E (0.93) | KDM4EHRH3ALDH1A1HTTATM | |
| Hydrochloric Acid SCHEMBL7176715 | 0.96 | KDM4E (0.93) | KDM4EHRH3ALDH1A1HTTATM | |
| Hydrochloric Acid SCHEMBL7174211 | 0.96 | KDM4E (0.93) | KDM4EHRH3ALDH1A1HTTATM | |
| Hydrochloric Acid SCHEMBL7171692 | 0.96 | KDM4E (0.93) | KDM4EHRH3ALDH1A1HTTATM | |
| Hydrochloric Acid SCHEMBL7181592 | 0.96 | KDM4E (0.93) | KDM4EHRH3ALDH1A1HTTATM | |
| SCHEMBL8855999 | 0.96 | KDM4E (1.00) | KDM4EHRH3ALDH1A1HTTATM | |
| SCHEMBL20410986 | 0.90 | KDM4E (0.87) | KDM4EHRH3ALDH1A1HTTATM | |
| SCHEMBL20410871 | 0.88 | KDM4E (0.84) | KDM4EHRH3ALDH1A1HTTATM | |
| SCHEMBL758966 | 0.87 | KDM4E (0.81) | KDM4EHRH3ALDH1A1HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |