Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MYC | P01106 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7173255 | 0.97 | KDM4E (0.70) | KDM4EHSD17B10MYCALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7183956 | 0.97 | KDM4E (0.70) | KDM4EHSD17B10MYCALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7179249 | 0.97 | KDM4E (0.70) | KDM4EHSD17B10MYCALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7179030 | 0.97 | KDM4E (0.70) | KDM4EHSD17B10MYCALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7172329 | 0.97 | KDM4E (0.70) | KDM4EHSD17B10MYCALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7183851 | 0.97 | KDM4E (0.70) | KDM4EHSD17B10MYCALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7176527 | 0.91 | KDM4E (0.57) | KDM4EHSD17B10MYCALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7171328 | 0.89 | KDM4E (0.55) | KDM4EHSD17B10MYCALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7174794 | 0.88 | KDM4E (0.57) | KDM4EHSD17B10MYCALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7181171 | 0.88 | KDM4E (0.57) | KDM4EHSD17B10MYCALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |