Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RARB | P10826 | 4/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218850 | 1.00 | PLA2G4B (0.48) | PLA2G4BSMN1; SMN2RARBTHRATHRB | |
| SCHEMBL7172585 | 1.00 | PLA2G4B (0.48) | PLA2G4BSMN1; SMN2RARBTHRATHRB | |
| SCHEMBL7171548 | 0.99 | PLA2G4B (0.49) | PLA2G4BSMN1; SMN2RARBTHRATHRB | |
| SCHEMBL7168526 | 0.98 | PLA2G4B (0.46) | PLA2G4BSMN1; SMN2RARBTHRATHRB | |
| SCHEMBL7167527 | 0.94 | PLA2G4B (0.53) | PLA2G4BSMN1; SMN2RARBTHRATHRB | |
| SCHEMBL8926782 | 0.94 | PLA2G4B (0.53) | PLA2G4BSMN1; SMN2RARBTHRATHRB | |
| SCHEMBL4270500 | 0.90 | PLA2G4B (0.52) | PLA2G4BSMN1; SMN2RARBTHRATHRB | |
| SCHEMBL8924412 | 0.90 | PLA2G4B (0.52) | PLA2G4BSMN1; SMN2RARBTHRATHRB | |
| SCHEMBL29382893 | 0.90 | PLA2G4B (0.52) | PLA2G4BSMN1; SMN2RARBTHRATHRB | |
| SCHEMBL8924946 | 0.88 | PLA2G4B (0.54) | PLA2G4BSMN1; SMN2RARBTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569504-B1 | Dimers of LC-like compounds in which the monomers are linked to each other through a high birefringence moiety (dimerization linker) | DISPLAYTECH, INC. | 2003-05-27 | — | — | US | disclosed |
| US-6139771-A | USEFUL IN ELECTOOPTICAL AND NON-LINEAR OPTICAL APPLICATIONS | DISPLAYTECH, INC. (US) | 2000-10-31 | — | — | US | disclosed |