SCHEMBL7173303

SCHEMBL7173303

CCCCCCC/C=C/COc1ccc(C(=O)OC)cc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.53
MAPT P10636 3/20 0.53
CNR1 P21554 5/20 0.50
CNR2 P34972 2/20 0.48
RAB9A P51151 3/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
PLA2G4B P0C869 1/20 0.47
NPC1 O15118 2/20 0.46
CASP1 P29466 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1330818 0.90 MAPT (0.62) MGLLMAPTCNR1RAB9ATP53
SCHEMBL7167817 0.89 MAPT (0.60) MGLLMAPTRAB9ATP53TSHR
SCHEMBL7166103 0.89 MAPT (0.64) MGLLMAPTRAB9ATP53TSHR
SCHEMBL8215064 0.88 MAPT (0.59) MGLLMAPTRAB9ATP53TSHR
SCHEMBL8216217 0.88 MAPT (0.59) MGLLMAPTRAB9ATP53TSHR
SCHEMBL7173323 0.87 RARB (0.63) MGLLMAPTRAB9ATP53TSHR
SCHEMBL7166673 0.86 TP53 (0.66) TP53TSHRPLA2G4B
SCHEMBL7166669 0.86 TP53 (0.66) TP53TSHRPLA2G4B
SCHEMBL7166119 0.86 MAPT (0.64) MAPTRAB9ATP53TSHRPLA2G4B
SCHEMBL5059128 0.85 MAPT (0.70) MAPTRAB9ANPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6569504-B1 Dimers of LC-like compounds in which the monomers are linked to each other through a high birefringence moiety (dimerization linker) DISPLAYTECH, INC. 2003-05-27 US disclosed
US-6139771-A USEFUL IN ELECTOOPTICAL AND NON-LINEAR OPTICAL APPLICATIONS DISPLAYTECH, INC. (US) 2000-10-31 US disclosed