SCHEMBL7166103

SCHEMBL7166103

CCCCC/C=C/CCCOc1ccc(C(=O)OC)cc1

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.64
RAB9A P51151 2/20 0.57
TP53 P04637 1/20 0.54
TSHR P16473 1/20 0.54
MMP1 P03956 1/20 0.53
PLA2G4B P0C869 1/20 0.52
MGLL Q99685 1/20 0.52
NPC1 O15118 2/20 0.51
CASP1 P29466 1/20 0.51
RARB P10826 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
ASAH2 Q9NR71 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1330818 0.99 MAPT (0.62) MAPTRAB9ATP53TSHRMMP1
SCHEMBL7167817 0.94 MAPT (0.60) MAPTRAB9ATP53TSHRMMP1
SCHEMBL7166119 0.94 MAPT (0.64) MAPTRAB9ATP53TSHRMMP1
SCHEMBL8215064 0.93 MAPT (0.59) MAPTRAB9ATP53TSHRPLA2G4B
SCHEMBL8216217 0.93 MAPT (0.59) MAPTRAB9ATP53TSHRPLA2G4B
SCHEMBL7173323 0.92 RARB (0.63) MAPTRAB9ATP53TSHRPLA2G4B
SCHEMBL7172057 0.90 RARB (0.60) MAPTRAB9ATP53TSHRPLA2G4B
SCHEMBL7171365 0.90 RARB (0.60) MAPTRAB9ATP53TSHRPLA2G4B
SCHEMBL7173364 0.90 RARB (0.60) MAPTRAB9ATP53TSHRPLA2G4B
SCHEMBL7173303 0.89 MGLL (0.53) MAPTRAB9ATP53TSHRPLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6569504-B1 Dimers of LC-like compounds in which the monomers are linked to each other through a high birefringence moiety (dimerization linker) DISPLAYTECH, INC. 2003-05-27 US disclosed
US-6139771-A USEFUL IN ELECTOOPTICAL AND NON-LINEAR OPTICAL APPLICATIONS DISPLAYTECH, INC. (US) 2000-10-31 US disclosed