Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7173300 | 1.00 | PPARA (0.48) | PPARATHRATHRBCYSLTR2CYSLTR1 | |
| SCHEMBL7167821 | 0.90 | THRA (0.54) | PPARATHRATHRBRARBPTPN11 | |
| SCHEMBL7167816 | 0.90 | THRA (0.54) | PPARATHRATHRBRARBPTPN11 | |
| SCHEMBL7166105 | 0.90 | THRA (0.53) | PPARATHRATHRBRARBPTPN11 | |
| SCHEMBL7166101 | 0.90 | THRA (0.53) | PPARATHRATHRBRARBPTPN11 | |
| SCHEMBL7166122 | 0.87 | THRA (0.53) | THRATHRBRARBPTPN11PLK1 | |
| SCHEMBL7166116 | 0.87 | THRA (0.53) | THRATHRBRARBPTPN11PLK1 | |
| SCHEMBL23748611 | 0.84 | HTT (0.41) | THRATHRBRARBPTPN11TP53 | |
| SCHEMBL28618808 | 0.84 | HTT (0.41) | THRATHRBRARBPTPN11TP53 | |
| SCHEMBL7166673 | 0.83 | TP53 (0.66) | RARBTP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6569504-B1 | Dimers of LC-like compounds in which the monomers are linked to each other through a high birefringence moiety (dimerization linker) | DISPLAYTECH, INC. | 2003-05-27 | — | — | US | disclosed |
| US-6139771-A | USEFUL IN ELECTOOPTICAL AND NON-LINEAR OPTICAL APPLICATIONS | DISPLAYTECH, INC. (US) | 2000-10-31 | — | — | US | disclosed |