Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 8/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7173434 | 0.93 | TNFRSF1A (0.37) | TNFRSF1AABCG2NPC1RAB9AMAPT | |
| SCHEMBL6040608 | 0.89 | ABCG2 (0.49) | TNFRSF1AABCG2NPC1RAB9AMAPT | |
| SCHEMBL6040613 | 0.89 | ABCG2 (0.49) | TNFRSF1AABCG2NPC1RAB9AMAPT | |
| SCHEMBL6788300 | 0.85 | ABCG2 (0.53) | TNFRSF1AABCG2NPC1RAB9AMAPT | |
| SCHEMBL6788295 | 0.85 | ABCG2 (0.53) | TNFRSF1AABCG2NPC1RAB9AMAPT | |
| SCHEMBL6794186 | 0.85 | ABCG2 (0.53) | TNFRSF1AABCG2NPC1RAB9AMAPT | |
| SCHEMBL6040661 | 0.79 | ABCG2 (0.45) | TNFRSF1AABCG2MAPTSMN1; SMN2DPP4 | |
| SCHEMBL6040664 | 0.79 | ABCG2 (0.45) | TNFRSF1AABCG2MAPTSMN1; SMN2DPP4 | |
| SCHEMBL6040602 | 0.69 | RXRA (0.36) | ALDH1A1CSNK2A1 | |
| SCHEMBL6040515 | 0.69 | TNFRSF1A (0.54) | TNFRSF1AABCG2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056727-A2 | PROCESS OF MAKING CHALCONE DERIVATIVES | ATHEROGENICS, INC. (US) | 2004-07-08 | — | — | WO | disclosed |