Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7176410 | 1.00 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7171153 | 0.97 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7175195 | 0.97 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7175821 | 0.97 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7171650 | 0.97 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7176406 | 0.97 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7182624 | 0.97 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7183038 | 0.97 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7175838 | 0.97 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7179118 | 0.97 | NPC1 (0.62) | NPC1MAPTRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |