Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7177501 | 0.97 | MAPT (0.43) | MAPTKMT2AMEN1NR4A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7178927 | 0.97 | MAPT (0.43) | MAPTKMT2AMEN1NR4A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7181632 | 0.97 | MAPT (0.43) | MAPTKMT2AMEN1NR4A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7173224 | 0.97 | MAPT (0.43) | MAPTKMT2AMEN1NR4A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7185097 | 0.97 | MAPT (0.43) | MAPTKMT2AMEN1NR4A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7182221 | 0.97 | MAPT (0.43) | MAPTKMT2AMEN1NR4A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7177162 | 0.88 | NR4A1 (0.43) | MAPTKMT2AMEN1NR4A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7174493 | 0.84 | NR4A1 (0.43) | MAPTKMT2AMEN1NR4A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7180426 | 0.84 | NR4A1 (0.43) | MAPTKMT2AMEN1NR4A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7183402 | 0.84 | NR4A1 (0.43) | MAPTKMT2AMEN1NR4A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |