Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 14/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174149 | 1.00 | CXCR3 (0.74) | CXCR3CYP2D6CCR1ALOX5EPHX2 | |
| SCHEMBL7174143 | 1.00 | CXCR3 (0.74) | CXCR3CYP2D6CCR1ALOX5EPHX2 | |
| SCHEMBL6313752 | 0.86 | CXCR3 (0.77) | CXCR3CYP2D6CCR1EPHX2NPC1 | |
| SCHEMBL6313755 | 0.86 | CXCR3 (0.77) | CXCR3CYP2D6CCR1EPHX2NPC1 | |
| SCHEMBL6313749 | 0.86 | CXCR3 (0.77) | CXCR3CYP2D6CCR1EPHX2NPC1 | |
| SCHEMBL22965169 | 0.85 | CXCR3 (1.00) | CXCR3CYP2D6CCR1EPHX2 | |
| SCHEMBL6314461 | 0.84 | CXCR3 (0.75) | CXCR3CYP2D6CCR1EPHX2NPC1 | |
| SCHEMBL6314469 | 0.84 | CXCR3 (0.75) | CXCR3CYP2D6CCR1EPHX2NPC1 | |
| SCHEMBL6314473 | 0.84 | CXCR3 (0.75) | CXCR3CYP2D6CCR1EPHX2NPC1 | |
| SCHEMBL6320011 | 0.83 | CXCR3 (0.70) | CXCR3CYP2D6CCR1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478359-A1 | PIPERIDIN-4-YL UREA DERIVATIVES AND RELATED COMPOUNDS AS CHEMOKINE RECEPTOR INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Celltech R & D Limited (GB) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003070242-A1 | PIPERIDIN-4-YL UREA DERIVATIVES AND RELATED COMPOUNDS AS CHEMOKINE RECEPTOR INHIBITORS FOR THE TREATMENT OF INFLAMMATORY DISEASES | CELLTECH R & D LIMITED (GB) | 2003-08-28 | — | — | WO | disclosed |