Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670070 | 0.93 | HTT (0.39) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9169632 | 0.91 | HTT (0.35) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL7181564 | 0.90 | MEN1 (0.54) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL7189533 | 0.90 | MEN1 (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9483196 | 0.90 | MEN1 (0.54) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL4921495 | 0.90 | MEN1 (0.54) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL983239 | 0.90 | MEN1 (0.54) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL9171491 | 0.88 | MEN1 (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL15673463 | 0.88 | MEN1 (0.52) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL28203082 | 0.86 | MEN1 (0.50) | HTTMEN1THRBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1290040-A2 | POLYALKYLENE GRAFTED CENTIPEDE POLYMERS | Bridgestone Corporation (JP) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001094425-A2 | POLYALKYLENE GRAFTED CENTIPEDE POLYMERS | BRIDGESTONE CORPORATION (JP) | 2001-12-13 | — | — | WO | disclosed |