SCHEMBL7189533

SCHEMBL7189533

CCCCOCCCCCCC[CH]CCCCCCCOCCCC

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.48
THRB P10828 1/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 1/20 0.48
MAPT P10636 1/20 0.48
TSHR P16473 4/20 0.48
CYP3A4 P08684 1/20 0.41
CES2 O00748 1/20 0.40
LPAR2 Q9HBW0 3/20 0.38
LPAR3 Q9UBY5 3/20 0.38
LPAR1 Q92633 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15673463 0.98 MEN1 (0.52) MEN1THRBHTTKMT2AMAPT
SCHEMBL4921495 0.95 MEN1 (0.54) MEN1THRBHTTKMT2AMAPT
SCHEMBL9483196 0.95 MEN1 (0.54) MEN1THRBHTTKMT2AMAPT
SCHEMBL7181564 0.95 MEN1 (0.54) MEN1THRBHTTKMT2AMAPT
SCHEMBL3631091 0.95 TSHR (0.48) MEN1THRBHTTKMT2AMAPT
SCHEMBL983239 0.95 MEN1 (0.54) MEN1THRBHTTKMT2AMAPT
SCHEMBL9171491 0.93 MEN1 (0.52) MEN1THRBHTTKMT2AMAPT
SCHEMBL8209749 0.91 MEN1 (0.42) MEN1THRBHTTKMT2AMAPT
SCHEMBL28203082 0.91 MEN1 (0.50) MEN1THRBHTTKMT2AMAPT
SCHEMBL7174308 0.90 HTT (0.43) MEN1THRBHTTKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1290040-A2 POLYALKYLENE GRAFTED CENTIPEDE POLYMERS Bridgestone Corporation (JP) 2003-03-12 EP disclosed
WO-2001094425-A2 POLYALKYLENE GRAFTED CENTIPEDE POLYMERS BRIDGESTONE CORPORATION (JP) 2001-12-13 WO disclosed