Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | MMP12 | P39900 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | STS | P08842 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455002 | 0.80 | CYP1A2 (0.37) | SERPINE1LMNAMEN1KMT2ARAB9A | |
| SCHEMBL28078408 | 0.79 | HDAC2 (0.46) | MMP9MMP12MMP1MMP2STS | |
| SCHEMBL8183007 | 0.77 | — | — | |
| SCHEMBL7193299 | 0.75 | — | — | |
| SCHEMBL11578150 | 0.74 | PTPN1 (0.36) | LMNA | |
| SCHEMBL43932 | 0.71 | — | — | |
| SCHEMBL1697290 | 0.71 | SERPINE1 (0.43) | SERPINE1MMP9MMP12MMP1MMP2 | |
| SCHEMBL1481724 | 0.70 | — | — | |
| SCHEMBL6960478 | 0.70 | — | — | |
| SCHEMBL43992 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334161-A1 | STRUCTURAL HOT MELT MATERIAL AND METHODS | L & L Products, Inc. (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2003022953-A1 | STRUCTURAL HOT MELT MATERIAL AND METHODS | L & L PRODUCTS, INC. (US) | 2003-03-20 | — | — | WO | disclosed |