SCHEMBL1697290

SCHEMBL1697290

O=C(OC1CC1)C1=CC(F)C1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 2/20 0.43
MAPT P10636 2/20 0.35
MMP9 P14780 3/20 0.33
MMP12 P39900 3/20 0.33
MMP1 P03956 2/20 0.33
KMT2A Q03164 2/20 0.33
MMP2 P08253 2/20 0.33
SCN1A P35498 2/20 0.33
SCN2A Q99250 2/20 0.33
SCN3A Q9NY46 2/20 0.33
MEN1 O00255 1/20 0.33
STS P08842 4/20 0.32
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
LMNA P02545 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7174485 0.71 SERPINE1 (0.46) SERPINE1MAPTMMP9MMP12MMP1
SCHEMBL27613024 0.67 SERPINE1 (0.61) SERPINE1MAPTKMT2ASCN1ASCN2A
SCHEMBL13674315 0.64 MEN1 (0.59) SERPINE1MAPTKMT2ASCN1ASCN2A
SCHEMBL3229154 0.64 MEN1 (0.59) SERPINE1MAPTKMT2ASCN1ASCN2A
SCHEMBL3229157 0.64 MEN1 (0.59) SERPINE1MAPTKMT2ASCN1ASCN2A
SCHEMBL208341 0.64 TSHR (0.53) SERPINE1MMP9MMP12MMP1KMT2A
SCHEMBL4453290 0.63 MEN1 (0.69) SERPINE1MAPTKMT2ASCN1ASCN2A
SCHEMBL1786140 0.63 MEN1 (0.69) SERPINE1MAPTKMT2ASCN1ASCN2A
SCHEMBL9470239 0.62 MMP9 (0.44) SERPINE1MAPTMMP9MMP12MMP1
SCHEMBL7993233 0.62 CES2 (0.50) SERPINE1KMT2ASCN1ASCN2ASCN3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2486600-A2 METHOD FOR MANUFACTURING MULTILAYER FILMS AND SOLAR PANEL BACKSHEETS FORMED THEREOF E. I. du Pont de Nemours and Company (US) 2012-08-15 EP disclosed
WO-2011044417-A2 METHOD FOR MANUFACTURING MULTILAYER FILMS AND SOLAR PANEL BACKSHEETS FORMED THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-04-14 WO disclosed