Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1R | P00736 | 9/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | F2 | P00734 | 2/20 | 0.73 |
| ▸ | KLK3 | P07288 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | ELANE | P08246 | 3/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | KLK1 | P06870 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10924688 | 0.84 | C1R (1.00) | C1RKMT2AMEN1MAPTF2 | |
| SCHEMBL17059024 | 0.82 | RAB9A (0.65) | C1RKMT2AMEN1MAPTF2 | |
| SCHEMBL912869 | 0.81 | MEN1 (0.60) | C1RKMT2AMEN1MAPTF2 | |
| SCHEMBL915069 | 0.81 | KLK3 (0.73) | C1RKMT2AMEN1MAPTF2 | |
| SCHEMBL914003 | 0.81 | KMT2A (1.00) | C1RKMT2AMEN1MAPTF2 | |
| SCHEMBL29370698 | 0.79 | KMT2A (0.74) | C1RKMT2AMEN1MAPTF2 | |
| SCHEMBL692758 | 0.79 | KMT2A (0.74) | C1RKMT2AMEN1MAPTF2 | |
| SCHEMBL914109 | 0.79 | C1R (0.74) | C1RKMT2AMEN1MAPTF2 | |
| SCHEMBL914314 | 0.78 | KMT2A (0.82) | C1RKMT2AMEN1MAPTF2 | |
| SCHEMBL913435 | 0.78 | C1R (0.73) | C1RKMT2AMEN1MAPTF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007955-A2 | BIPHENYL APURINIC/APYRIMIDINIC SITE ENDONUCLEASE INHIBITORS TO TREAT CANCER | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-01-30 | — | — | WO | claimed |