Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | RHOA | P61586 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183970 | 0.94 | CYP3A4 (0.48) | CYP3A4ALDH1A1HSD17B10TSHRCA1 | |
| SCHEMBL436695 | 0.93 | CYP3A4 (0.47) | CYP3A4ALDH1A1HSD17B10TSHRCA1 | |
| SCHEMBL7174680 | 0.93 | CYP3A4 (0.50) | CYP3A4ALDH1A1HSD17B10TSHRCA1 | |
| SCHEMBL20695812 | 0.89 | CYP3A4 (0.50) | CYP3A4ALDH1A1HSD17B10TSHRCA1 | |
| SCHEMBL20183947 | 0.85 | CYP3A4 (0.53) | CYP3A4ALDH1A1HSD17B10TSHRCA1 | |
| SCHEMBL4543339 | 0.81 | CYP3A4 (0.43) | CYP3A4ALDH1A1HSD17B10TSHRCA1 | |
| SCHEMBL12192391 | 0.78 | TSHR (0.47) | CYP3A4ALDH1A1HSD17B10TSHRMAPK1 | |
| SCHEMBL28379868 | 0.77 | CYP3A4 (0.43) | CYP3A4ALDH1A1HSD17B10TSHRCA1 | |
| SCHEMBL2323915 | 0.76 | CYP3A4 (0.62) | CYP3A4ALDH1A1HSD17B10TSHRCA1 | |
| Allylamine SCHEMBL20567905 | 0.75 | ALDH1A1 (0.39) | ALDH1A1TSHRMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328560-A2 | PLASTIC LENS COMPOSITION, PLASTIC LENS, AND PROCESS FOR PRODUCING THE PLASTIC LENS | Showa Denko K.K. (JP) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002026843-A2 | PLASTIC LENS COMPOSITION, PLASTIC LENS, AND PROCESS FOR PRODUCING THE PLASTIC LENS | SHOWA DENKO K. K. (JP) | 2002-04-04 | — | — | WO | disclosed |