SCHEMBL7174885

SCHEMBL7174885

COCC1(C(=O)O)C=CC=C(N)C1.Cc1ccc(C)o1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP3A4 P08684 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7175270 0.75 TDP1 (0.31) MAPTALDH1A1
SCHEMBL11544898 0.73
SCHEMBL7171035 0.73 ALOX5 (0.33) KDM4EMAPTALDH1A1
SCHEMBL830393 0.73 TSHR (0.30)
SCHEMBL7160266 0.71 KDM4E (0.31) KDM4E
SCHEMBL7553639 0.71 POLB (0.31)
SCHEMBL29249163 0.62
SCHEMBL713734 0.60 GRM4 (0.30)
Carbamic Acid SCHEMBL28595840 0.60 TDP1 (0.61) KDM4EMAPTMEN1ALDH1A1KMT2A
Bicarbonate SCHEMBL9195144 0.59 TDP1 (0.69) KDM4EMAPTMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6506913-B2 Wood preservatives SANKYO COMPANY, LIMITED (JP) 2003-01-14 US disclosed
US-20020091154-A1 Dimethylfurancarboxyanilide derivatives SANKYO COMPANY LIMITED (JP) 2002-07-11 US disclosed
US-6380247-B2 A WOOD PRESERVATIVE; POTENTIATION WHEN MIXED WITH AT LEAST ONE OF 3-BROMO-2,3-DIIODO-2-PROPENYL-ETHYLCARBAMATE, 3-IODO-2-PROPYNYLBUTYL-CARBAMATE AND 4-CHLOROPHENYL-3-IODOPROPARGYLFORMAL; MICROBIOCIDES SANKYO COMPANY, LIMITED (JP) 2002-04-30 US disclosed
US-20010000184-A1 Dimethylfurancarboxyanilide derivatives SANKYO COMPANY, LIMITED 2001-04-05 US disclosed
US-5977168-A 2,5-DIMETHYLFURAN-3-CARBOXYANILIDE DERIVATIVES SANKYO COMPANY, LIMITED (JP) 1999-11-02 US disclosed
EP-0755927-A1 DIMETHYLFURANCARBOXANILIDE DERIVATIVE SANKYO COMPANY LIMITED (JP) 1997-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020091154-A1 Dimethylfurancarboxyanilide derivatives C9, CBR1, CBR3 KDM4E 238/4885MAPT 3855/4885MEN1 1504/4885
US-20010000184-A1 Dimethylfurancarboxyanilide derivatives C9, CBR1, CBR3 KDM4E 238/4885MAPT 3855/4885MEN1 1504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.