Ether — predicted protein targets

Known targets — ChEMBL curated mechanism

MMP1 MMP13 MMP7 MMP8 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	3/20	0.46

▸	TSHR	P16473	2/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Ether SCHEMBL2112315	0.97	ALDH1A1 (0.48)	ALDH1A1TSHR
Ether SCHEMBL250891	0.97	ALDH1A1 (0.48)	ALDH1A1TSHR
Ether SCHEMBL8958539	0.97	ALDH1A1 (0.48)	ALDH1A1TSHR
Ether SCHEMBL43391	0.97	ALDH1A1 (0.48)	ALDH1A1TSHR
Ether SCHEMBL1070562	0.97	ALDH1A1 (0.48)	ALDH1A1TSHR
Ether SCHEMBL9184166	0.94	ALDH1A1 (0.46)	ALDH1A1TSHR
Ether SCHEMBL27869584	0.94	ALDH1A1 (0.43)	ALDH1A1TSHR
Ether SCHEMBL9445610	0.92	ALDH1A1 (0.43)	ALDH1A1TSHR
Ether SCHEMBL4837373	0.92	ALDH1A1 (0.43)	ALDH1A1TSHR
Hexane SCHEMBL7764654	0.87	SMN1; SMN2 (0.43)	ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6583101-B1	Synergystic solvent concentrates comprising carbo and acyclic hydroxy ethers, used as antisoilants for substrate surfaces such as floors, photoresists, paints, inks, woven or nonwoven fabrics	ECOLAB INC.	2003-06-24	—	—	US	claimed