Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL27648150 | 0.97 | LMNA (0.45) | LMNAEGLN1ALKBH5SUCNR1ABCC4 | |
| Adipic Acid SCHEMBL7135978 | 0.90 | ABCC4 (0.58) | LMNAABCC4MAPTTSHRNFKB1 | |
| Bicarbonate SCHEMBL1206563 | 0.86 | CA1 (0.41) | LMNAABCC4MAPTTSHRMEN1 | |
| SCHEMBL222657 | 0.85 | — | — | |
| Adipic Acid SCHEMBL27803366 | 0.84 | ABCC4 (0.52) | LMNAABCC4MAPTTSHRNFKB1 | |
| Glutarate SCHEMBL28310800 | 0.84 | ABCC4 (0.47) | LMNAABCC4MAPTTSHRNFKB1 | |
| Glycolic Acid SCHEMBL4345632 | 0.84 | CA1 (0.37) | LMNAABCC4MAPTTSHRMEN1 | |
| Oxalic Acid SCHEMBL28528613 | 0.83 | CA1 (0.39) | LMNAABCC4MAPTTSHRMEN1 | |
| Hydrogen Peroxide SCHEMBL11812678 | 0.83 | — | — | |
| Succinic Acid SCHEMBL28486194 | 0.83 | ABCC4 (0.36) | LMNAEGLN1ALKBH5SUCNR1ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117529517-A | Thermoset polymer foam and method of making same | 普兰迪斯控股有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-113081887-A | Scalp care shampoo composition with high sea salt content and preparation method thereof | 佩莱品牌管理有限公司 | 2021-07-09 | — | — | CN | claimed |
| CN-112120944-A | Transparent bubble bath oil for helping skin barrier function recovery and preparation method thereof | 广州荃智美肤生物科技研究院有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-110527486-A | Resistance to ultraviolet organosilicon adhesive of one kind and preparation method thereof | DING AISHUN | 2019-12-03 | — | — | CN | claimed |
| CN-117529517-A | Thermoset polymer foam and method of making same | 普兰迪斯控股有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117042752-A | Compositions from bacterial organisms and uses thereof | 自由生物安全公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-115317408-A | Transparent foaming bath oil with all-natural source and preparation method thereof | 诺斯贝尔化妆品股份有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-113081887-A | Scalp care shampoo composition with high sea salt content and preparation method thereof | 佩莱品牌管理有限公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-112120944-A | Transparent bubble bath oil for helping skin barrier function recovery and preparation method thereof | 广州荃智美肤生物科技研究院有限公司 | 2020-12-25 | — | — | CN | disclosed |
| CN-110527486-A | Resistance to ultraviolet organosilicon adhesive of one kind and preparation method thereof | DING AISHUN | 2019-12-03 | — | — | CN | disclosed |
| US-10428194-B2 | Modified acrylic resin cured product, and laminate thereof, and production methods therefor | MITSUI CHEMICALS, INC. (JP) | 2019-10-01 | — | — | US | disclosed |
| EP-3263635-B1 | MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR | MITSUI CHEMICALS INC (JP) | 2019-09-18 | — | — | EP | disclosed |
| EP-3270192-A1 | HYDROPHILIC SINGLE-LAYER FILM HAVING OPTICAL FUNCTIONALITY, AND LAMINATE THEREOF | Mitsui Chemicals, Inc. (JP) | 2018-01-17 | — | — | EP | disclosed |
| EP-3263635-A1 | MODIFIED ACRYLIC RESIN CURED PRODUCT, AND LAMINATE THEREOF, AND PRODUCTION METHODS THEREFOR | Mitsui Chemicals, Inc. (JP) | 2018-01-03 | — | — | EP | disclosed |
| CN-107430213-A | Hydrophilic optical feature monofilm and its layered product | 三井化学株式会社 | 2017-12-01 | — | — | CN | disclosed |
| CN-107250226-A | Acrylic resin modified solidfied material and its layered product and their manufacture method | 三井化学株式会社 | 2017-10-13 | — | — | CN | disclosed |
| EP-3081578-A1 | COMPOSITION FOR HYDROPHILIC CURED PRODUCT | Mitsui Chemicals, Inc. (JP) | 2016-10-19 | — | — | EP | disclosed |
| CN-105814092-A | Composition for hydrophilic cured product | 三井化学株式会社 | 2016-07-27 | — | — | CN | disclosed |
| CN-1494408-A | Delivery of active agents for shelf stable products by multiple emulsions | — | 2004-05-05 | — | — | CN | disclosed |
| US-6568856-B2 | Rolling bearing | NSK LTD. (JP) | 2003-05-27 | — | — | US | disclosed |