Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 19/20 | 0.73 |
| ▸ | PGGT1B | P53609 | 18/20 | 0.73 |
| ▸ | FNTB | P49356 | 17/20 | 0.66 |
| ▸ | DNAJA1 | P31689 | 1/20 | 0.66 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186917 | 0.94 | FNTA (0.72) | FNTAPGGT1BFNTBDNAJA1KCNH2 | |
| SCHEMBL7176101 | 0.88 | FNTA (0.63) | FNTAPGGT1BFNTBDNAJA1KCNH2 | |
| SCHEMBL7159206 | 0.84 | FNTA (1.00) | FNTAPGGT1BFNTBDNAJA1KCNH2 | |
| SCHEMBL7160364 | 0.82 | FNTA (0.79) | FNTAPGGT1BFNTBDNAJA1KCNH2 | |
| SCHEMBL3516578 | 0.79 | FNTA (1.00) | FNTAPGGT1BFNTBDNAJA1KCNH2 | |
| SCHEMBL29564445 | 0.79 | FNTA (1.00) | FNTAPGGT1BFNTBDNAJA1KCNH2 | |
| SCHEMBL7635537 | 0.79 | FNTA (1.00) | FNTAPGGT1BFNTBDNAJA1KCNH2 | |
| SCHEMBL7631374 | 0.79 | FNTA (0.83) | FNTAPGGT1BFNTBDNAJA1KCNH2 | |
| Hydrochloric Acid SCHEMBL7637950 | 0.78 | FNTA (0.81) | FNTAPGGT1BFNTBDNAJA1KCNH2 | |
| SCHEMBL6433388 | 0.76 | FNTA (0.82) | FNTAPGGT1BFNTBDNAJA1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562823-B1 | Inhibition of farnesyl-protein transferase has been shown to block the growth of Ras-transformed cells in soft agar | MERCK & CO., INC. | 2003-05-13 | — | — | US | claimed |
| US-6562823-B1 | Inhibition of farnesyl-protein transferase has been shown to block the growth of Ras-transformed cells in soft agar | MERCK & CO., INC. | 2003-05-13 | — | — | US | disclosed |