SCHEMBL7175442

SCHEMBL7175442

CCOCCOc1cc(OCCOCC)c(PC(=O)c2c(Cl)cccc2OC)c(OCCOCC)c1.[LiH]

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.42
MAPT P10636 5/20 0.39
LMNA P02545 2/20 0.39
HPGD P15428 2/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
FFAR1 O14842 2/20 0.36
ELANE P08246 2/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7190024 0.94 L3MBTL1 (0.43) L3MBTL1MAPTLMNAALDH1A1FFAR1
SCHEMBL7189992 0.93 MAPT (0.42) L3MBTL1MAPTLMNAALDH1A1SMN1; SMN2
SCHEMBL7186427 0.90 ELANE (0.43) L3MBTL1MAPTALDH1A1SMN1; SMN2NPC1
SCHEMBL7180843 0.90 L3MBTL1 (0.42) L3MBTL1MAPTLMNAHPGDALDH1A1
SCHEMBL7180509 0.89 FFAR1 (0.40) L3MBTL1MAPTLMNAALDH1A1RAB9A
SCHEMBL7183569 0.89 MAPT (0.42) L3MBTL1MAPTSMN1; SMN2ELANECA12
SCHEMBL7177969 0.88 MAPT (0.41) L3MBTL1MAPTELANETDP1
SCHEMBL7189482 0.88 SMN1; SMN2 (0.45) MAPTLMNAHPGDALDH1A1SMN1; SMN2
SCHEMBL7182538 0.88 L3MBTL1 (0.43) L3MBTL1MAPTLMNAHPGDALDH1A1
SCHEMBL7190076 0.87 PPARA (0.42) L3MBTL1MAPTLMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 L3MBTL1 302/4885MAPT 4870/4885LMNA 3241/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 L3MBTL1 126/4885MAPT 4859/4885LMNA 3247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.