Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2710052 | 1.00 | PREP (0.46) | PREPHSD17B10UCHL1GPR119NR1H2 | |
| SCHEMBL2708283 | 1.00 | PREP (0.46) | PREPHSD17B10UCHL1GPR119NR1H2 | |
| SCHEMBL8272240 | 0.85 | HSD17B10 (0.44) | PREPHSD17B10NR1H2 | |
| SCHEMBL11950753 | 0.84 | PREP (0.40) | PREPHSD17B10UCHL1NR1H2NR1H3 | |
| SCHEMBL2709883 | 0.84 | PREP (0.51) | PREPHSD17B10NR1H2CYP1A2POLB | |
| SCHEMBL2708794 | 0.84 | PREP (0.51) | PREPHSD17B10NR1H2CYP1A2POLB | |
| SCHEMBL8272248 | 0.82 | RECQL (0.48) | PREPHSD17B10UCHL1GPR119NR1H2 | |
| SCHEMBL2708115 | 0.82 | PREP (0.45) | PREPHSD17B10UCHL1NR1H2DPP4 | |
| SCHEMBL8990042 | 0.81 | HSD17B10 (0.38) | HSD17B10UCHL1NR1H2NR1H3CYP1A2 | |
| SCHEMBL7143154 | 0.81 | HSD17B10 (0.38) | HSD17B10UCHL1NR1H2NR1H3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1308439-A1 | PROLINE DERIVATIVES AND USE THEREOF AS DRUGS | WELFIDE CORPORATION (JP) | 2003-05-07 | — | — | EP | disclosed |