Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.55 |
| ▸ | PRKACA | P17612 | 3/20 | 0.55 |
| ▸ | GSK3B | P49841 | 3/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.53 |
| ▸ | OGFRL1 | Q5TC84 | 8/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7175623 | 0.99 | RPS6KB1 (0.56) | RPS6KB1ROCK1PRKACAGSK3BCYP11B2 | |
| Hydrochloric Acid SCHEMBL7182425 | 0.97 | RPS6KB1 (0.55) | RPS6KB1ROCK1PRKACAGSK3BCYP11B2 | |
| Hydrochloric Acid SCHEMBL7177855 | 0.97 | RPS6KB1 (0.55) | RPS6KB1ROCK1PRKACAGSK3BCYP11B2 | |
| Hydrochloric Acid SCHEMBL7171351 | 0.97 | RPS6KB1 (0.55) | RPS6KB1ROCK1PRKACAGSK3BCYP11B2 | |
| Hydrochloric Acid SCHEMBL7175579 | 0.97 | RPS6KB1 (0.55) | RPS6KB1ROCK1PRKACAGSK3BCYP11B2 | |
| Hydrochloric Acid SCHEMBL7175652 | 0.97 | RPS6KB1 (0.55) | RPS6KB1ROCK1PRKACAGSK3BCYP11B2 | |
| Hydrochloric Acid SCHEMBL7176172 | 0.97 | RPS6KB1 (0.55) | RPS6KB1ROCK1PRKACAGSK3BCYP11B2 | |
| Hydrochloric Acid SCHEMBL7175207 | 0.96 | RPS6KB1 (0.56) | RPS6KB1ROCK1PRKACAGSK3BCYP11B2 | |
| Hydrochloric Acid SCHEMBL7185555 | 0.96 | RPS6KB1 (0.56) | RPS6KB1ROCK1PRKACAGSK3BCYP11B2 | |
| Hydrochloric Acid SCHEMBL7182759 | 0.96 | RPS6KB1 (0.56) | RPS6KB1ROCK1PRKACAGSK3BCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |