Tetraphenylphosphonium

Tetraphenylphosphonium

SCHEMBL7176299

[O-]P(O)O.c1ccc([P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.38
TDP1 Q9NUW8 3/20 0.36
CYP3A4 P08684 2/20 0.36
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 4/20 0.35
TAS2R38 P59533 3/20 0.35
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
TSHR P16473 2/20 0.33
CYP1A2 P05177 2/20 0.33
IDO1 P14902 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
NOX1 Q9Y5S8 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraphenylphosphonium SCHEMBL7176472 0.88 HIF1A (0.41) HIF1ATDP1CYP3A4ALDH1A1HSD17B10
Tetraphenylphosphonium SCHEMBL7176292 0.86 HIF1A (0.39) HIF1ATDP1CYP3A4ALDH1A1HSD17B10
Tetraphenylphosphonium SCHEMBL7170399 0.86 HIF1A (0.39) HIF1ATDP1CYP3A4ALDH1A1HSD17B10
Tetraphenylphosphonium SCHEMBL29362652 0.82 HIF1A (0.50) HIF1ATDP1ALDH1A1HSD17B10TSHR
Tetraphenylphosphonium SCHEMBL49763 0.80 HIF1A (0.39) HIF1ATDP1CYP3A4ALDH1A1HSD17B10
Tetraphenylphosphonium SCHEMBL2870352 0.79 HIF1A (0.43) HIF1ATDP1CYP3A4ALDH1A1HSD17B10
Tetraphenylphosphonium SCHEMBL7179664 0.79 CYP3A4 (0.46) HIF1ATDP1CYP3A4ESR1ESR2
Tetraphenylphosphonium SCHEMBL19921940 0.78 HIF1A (0.47) HIF1ATDP1ALDH1A1HSD17B10TSHR
Tetraphenylphosphonium SCHEMBL9638111 0.78 HIF1A (0.47) HIF1ATDP1ALDH1A1HSD17B10TSHR
Tetraphenylphosphonium SCHEMBL158514 0.78 HIF1A (0.47) HIF1ATDP1ALDH1A1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030195329-A1 Aromatic polycarbonate, composition thereof , and use TEIJIN LIMITED (JP) 2003-10-16 US disclosed
EP-1275694-A1 AROMATIC POLYCARBONATE COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2003-01-15 EP disclosed
US-20020103328-A1 Aromatic polycarbonate composition, production process therefor and molded product thereof TEIJIN LIMITED 2002-08-01 US disclosed