SCHEMBL7176341

SCHEMBL7176341

CCCC1(C(O)C/C=C/[C@H]2[C@H](O)CC(=O)[C@@H]2CC#CCCCC(=O)O)CCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 5/20 0.75
PTGER2 P43116 5/20 0.75
PTGER3 P43115 2/20 0.44
PTGER4 P35408 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13143656 0.86 PTGIR (1.00) PTGIRPTGER2PTGER4
SCHEMBL13951097 0.86 PTGIR (1.00) PTGIRPTGER2PTGER4
SCHEMBL14273618 0.86 PTGIR (1.00) PTGIRPTGER2PTGER4
SCHEMBL23352984 0.86 PTGIR (1.00) PTGIRPTGER2PTGER4
SCHEMBL13179799 0.86 PTGIR (1.00) PTGIRPTGER2PTGER4
SCHEMBL23352757 0.86 PTGIR (1.00) PTGIRPTGER2PTGER4
SCHEMBL23352912 0.84 PTGIR (0.77) PTGIRPTGER2PTGER3PTGER4
SCHEMBL23352995 0.84 PTGIR (0.77) PTGIRPTGER2PTGER3PTGER4
SCHEMBL23352556 0.84 PTGIR (0.77) PTGIRPTGER2PTGER3PTGER4
SCHEMBL7176984 0.84 PTGIR (0.77) PTGIRPTGER2PTGER3PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0860430-B1 Omega-cycloalkyl-prostaglandin E2 derivatives ONO PHARMACEUTICAL CO (JP) 2002-06-12 EP claimed
US-6110969-A Cycloalkyl-prostaglandin E2 derivatives ONO PHARMACEUTICAL CO. LTD. (JP) 2000-08-29 US claimed
EP-0860430-A2 Omega-cycloalkyl-prostaglandin E2 derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1998-08-26 EP claimed
US-6576785-B1 ω-cycloalkyl-prostaglandin E2 derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 2003-06-10 US disclosed
EP-0860430-B1 Omega-cycloalkyl-prostaglandin E2 derivatives ONO PHARMACEUTICAL CO (JP) 2002-06-12 EP disclosed
US-6110969-A Cycloalkyl-prostaglandin E2 derivatives ONO PHARMACEUTICAL CO. LTD. (JP) 2000-08-29 US disclosed
EP-0860430-A2 Omega-cycloalkyl-prostaglandin E2 derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1998-08-26 EP disclosed