Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 5/20 | 1.00 |
| ▸ | PTGER2 | P43116 | 4/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | RARB | P10826 | 1/20 | 0.59 |
| ▸ | RARG | P13631 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23352984 | 1.00 | PTGIR (1.00) | PTGIRPTGER2TSHRPTGER4MEN1 | |
| SCHEMBL13179799 | 1.00 | PTGIR (1.00) | PTGIRPTGER2TSHRPTGER4MEN1 | |
| SCHEMBL13143656 | 1.00 | PTGIR (1.00) | PTGIRPTGER2TSHRPTGER4MEN1 | |
| SCHEMBL23352757 | 1.00 | PTGIR (1.00) | PTGIRPTGER2TSHRPTGER4MEN1 | |
| SCHEMBL13951097 | 1.00 | PTGIR (1.00) | PTGIRPTGER2TSHRPTGER4MEN1 | |
| SCHEMBL14366538 | 0.91 | PTGIR (0.84) | PTGIRPTGER2TSHRPTGER4MEN1 | |
| SCHEMBL7587667 | 0.91 | PTGIR (0.84) | PTGIRPTGER2TSHRPTGER4MEN1 | |
| Butaprost SCHEMBL23353211 | 0.90 | PTGIR (1.00) | PTGIRPTGER2TSHRPTGER4MEN1 | |
| Butaprost SCHEMBL23352571 | 0.90 | PTGIR (1.00) | PTGIRPTGER2TSHRPTGER4MEN1 | |
| Butaprost SCHEMBL16335459 | 0.90 | PTGIR (1.00) | PTGIRPTGER2TSHRPTGER4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139435-A1 | PROSTAGLANDIN ANALOGS AND USES THEREOF | Lifex Biolabs, Inc. | 2021-05-13 | — | — | US | disclosed |
| EP-2818484-A1 | Synergistic combination of an anti-IgE antibody and an EP2 receptor agonist | Universitat Autònoma de Barcelona (ES) | 2014-12-31 | — | — | EP | disclosed |
| WO-2014206808-A1 | SYNERGISTIC COMBINATION OF AN ANTI-IGE ANTIBODY AND AN EP2 RECEPTOR AGONIST | UNIVERSITAT AUTONOMA DE BARCELONA (ES) | 2014-12-31 | — | — | WO | disclosed |
| US-20080045596-A1 | Ep2 Receptor Agonists | ASTERAND, INC. | 2008-02-21 | — | — | US | disclosed |
| US-20080045596-A1 | Ep2 Receptor Agonists | ASTERAND, INC. | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139435-A1 | PROSTAGLANDIN ANALOGS AND USES THEREOF | PTGDR, NR3C1, PTGIR | PTGIR 3/4885PTGER2 18/4885TSHR 218/4885 |
| US-20080045596-A1 | Ep2 Receptor Agonists | PTGER2, PTGER1, PTGER3 | PTGIR 4/4885PTGER2 1/4885TSHR 358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.