SCHEMBL7176355

SCHEMBL7176355

[Li]CCCN1CCC(C)CC(C)(C)C1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
MITF O75030 1/20 0.34
KMT2A Q03164 1/20 0.34
CARM1 Q86X55 1/20 0.33
PRMT6 Q96LA8 1/20 0.33
PRMT1 Q99873 1/20 0.33
PRMT8 Q9NR22 1/20 0.33
SIGMAR1 Q99720 6/20 0.33
GNAI3 P08754 1/20 0.31
GNAO1 P09471 1/20 0.31
GNAI1 P63096 1/20 0.31
KDM4E B2RXH2 1/20 0.31
RECQL P46063 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11215268 0.82 GNAO1 (0.51) SIGMAR1GNAI3GNAO1GNAI1
SCHEMBL11204905 0.82 GNAO1 (0.51) SIGMAR1GNAI3GNAO1GNAI1
SCHEMBL10709150 0.82 GNAO1 (0.51) SIGMAR1GNAI3GNAO1GNAI1
SCHEMBL12124973 0.77 SMN1; SMN2 (0.37) MEN1MITFKMT2ACARM1PRMT6
SCHEMBL18901501 0.70
SCHEMBL23828682 0.65 CARM1 (0.60) CARM1PRMT6PRMT1PRMT8SIGMAR1
SCHEMBL7170601 0.65 HRH3 (0.48) KDM4EHTR7
SCHEMBL20830066 0.63 MEN1 (0.30) MEN1MITFKMT2A
SCHEMBL20979241 0.62
SCHEMBL4737517 0.62 CARM1 (0.52) CARM1PRMT6PRMT1PRMT8SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894800-B1 Aliphatic solutions of aminoalkyllithium compounds BRIDGESTONE CORP (JP) 2003-03-12 EP claimed
EP-0894800-B1 Aliphatic solutions of aminoalkyllithium compounds BRIDGESTONE CORP (JP) 2003-03-12 EP disclosed
US-6046288-A REDUCING ALIPHATIC SOLVENT AMOUNT NEEDED FOR MAINTAINING AMINOALKYLLITHIUM INITIATORS IN SOLUTION BY COMBINING A CYCLIC AMINOALKYLLITHIUM COMPOUND OF GIVEN FORMULA WITH A DISSIMILAR LITHIOAMINE USEFUL IN ANIONIC POLYMERIZATION BRIDGESTONE CORPORATION (JP) 2000-04-04 US disclosed
US-5935893-A MIXTURE CONTAINING ANOTHER LITHIOAMINE COMPOUND; REDUCING AMOUNT OF SOLVENT NEEDED BRIDGESTONE CORPORATION (JP) 1999-08-10 US disclosed