Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7176599 | 0.97 | MAPT (0.58) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7181271 | 0.97 | MAPT (0.58) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7175471 | 0.97 | MAPT (0.58) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7176400 | 0.97 | MAPT (0.58) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7175896 | 0.97 | MAPT (0.58) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7182629 | 0.97 | MAPT (0.58) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL14154786 | 0.97 | MAPT (0.61) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL28573138 | 0.97 | MAPT (0.61) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL6712559 | 0.97 | MAPT (0.61) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL15842376 | 0.85 | MAPT (0.58) | MAPTNPC1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |