Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 2/20 | 0.50 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL5086905 | 1.00 | BDKRB2 (0.50) | BDKRB2CSNK1EDNM1SIGMAR1MEN1 | |
| Bromide SCHEMBL5086824 | 1.00 | BDKRB2 (0.50) | BDKRB2CSNK1EDNM1SIGMAR1MEN1 | |
| Bromide SCHEMBL15753684 | 1.00 | BDKRB2 (0.50) | BDKRB2CSNK1EDNM1SIGMAR1MEN1 | |
| Bromide SCHEMBL5086842 | 1.00 | BDKRB2 (0.50) | BDKRB2CSNK1EDNM1SIGMAR1MEN1 | |
| Bromide SCHEMBL5084788 | 1.00 | BDKRB2 (0.50) | BDKRB2CSNK1EDNM1SIGMAR1MEN1 | |
| Bromide SCHEMBL5088275 | 1.00 | BDKRB2 (0.50) | BDKRB2CSNK1EDNM1SIGMAR1MEN1 | |
| Bromide SCHEMBL5091956 | 1.00 | BDKRB2 (0.50) | BDKRB2CSNK1EDNM1SIGMAR1MEN1 | |
| Bromide SCHEMBL5088634 | 1.00 | BDKRB2 (0.50) | BDKRB2CSNK1EDNM1SIGMAR1MEN1 | |
| Bromide SCHEMBL723732 | 1.00 | BDKRB2 (0.50) | BDKRB2CSNK1EDNM1SIGMAR1MEN1 | |
| Bromide SCHEMBL27901149 | 1.00 | BDKRB2 (0.50) | BDKRB2CSNK1EDNM1SIGMAR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109439140-A | A kind of ion implanting composite coating anti-bacteria stainless steel water pipe | 福州盛世凌云环保科技有限公司 | 2019-03-08 | — | — | CN | claimed |
| CN-107903887-A | Excessive phase shale gas fracturing fluid in a kind of sea land and preparation method and application | 陕西森瑞石油技术开发有限公司 | 2018-04-13 | — | — | CN | claimed |
| US-8936728-B2 | Chemicals for oil spill cleanup | ANLON SOLUTIONS, LLC | 2015-01-20 | — | — | US | claimed |
| US-20120048809-A1 | Chemicals for Oil Spill Cleanup | ANLON SOLUTIONS, LLC | 2012-03-01 | — | — | US | claimed |
| WO-2024190910-A1 | ONE-COMPONENT CURABLE COATING COMPOSITION | 関西ペイント株式会社 | 2024-09-19 | — | — | WO | disclosed |
| CN-108485058-B | A kind of preparation method for the easy-stripping type laminar nano basic zirconium phosphate that size is controllable | 华南理工大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-110156217-A | A kind of processing method of rare earth processing waste water | 中铝稀土（宜兴）有限公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-110115266-A | A kind of Compound Hydrogen Peroxide Disinfectant and preparation method thereof | 肇庆大华农生物药品有限公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-110115271-A | A kind of compound disinfectant with hydrogen peroxide dilution, purposes and the method for egg surface sterilization | 肇庆大华农生物药品有限公司 | 2019-08-13 | — | — | CN | disclosed |
| CN-109837544-A | Corrosion and scale inhibitor and preparation method thereof | 中国石油天然气股份有限公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-109826051-A | A kind of single-component water-based organosilicon paper mould release and preparation method thereof | 上海楚艺佳有机硅材料有限公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-109440476-A | Water repellent fabric finishing agent, water repellent fabric preparation method and water repellent fabric and application | 五邑大学 | 2019-03-08 | — | — | CN | disclosed |
| US-8936728-B2 | Chemicals for oil spill cleanup | ANLON SOLUTIONS, LLC | 2015-01-20 | — | — | US | disclosed |
| CN-102816461-B | Quaternary ammonium cation and quaternary phosphonium cation-containing modified clay, its preparation and application | JINAN UNIVERSITY (CN) | 2014-10-29 | — | — | CN | disclosed |
| CN-102816461-A | Quaternary ammonium cation and quaternary phosphonium cation-containing modified clay, its preparation and application | UNIV JINAN | 2012-12-12 | — | — | CN | disclosed |
| US-20120048809-A1 | Chemicals for Oil Spill Cleanup | ANLON SOLUTIONS, LLC | 2012-03-01 | — | — | US | disclosed |
| US-8048491-B2 | 2-coat-1-bake system; an acrylic-type acid and/or acrylic-type anhydride, an epoxy-functional acrylic resin, and a glycol ether solvent; improved workability, electrostatic coatability, and gloss; clear coat paints | KANSAI PAINT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |
| US-20090087667-A1 | Multilayer coating film-forming method | KANSAI PAINT CO., LTD. | 2009-04-02 | — | — | US | disclosed |
| US-20080268256-A1 | Multilayer coating film- forming method | KANSAI PAINT CO., LTD. | 2008-10-30 | — | — | US | disclosed |
| US-20080214386-A1 | Stability; easily separated from solution; surface treatment of catalyst with Group seven compound; reacting epoxide with carbon dioxide | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2008-09-04 | — | — | US | disclosed |