SCHEMBL7177286

SCHEMBL7177286

CCCCC(CC)(CC)CCC

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.33
FDPS P14324 1/20 0.32
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18600102 0.94 TSHR (0.35) TSHRLMNATHRBFDPSESR1
SCHEMBL5070254 0.94 TSHR (0.35) TSHRLMNATHRBFDPSESR1
SCHEMBL16286664 0.94 TSHR (0.40) TSHRLMNATHRBFDPSESR1
SCHEMBL5049921 0.91 TSHR (0.39) TSHRLMNATHRBFDPS
SCHEMBL8895789 0.88 TSHR (0.37) TSHRTHRBFDPS
SCHEMBL1116134 0.88 TSHR (0.41) TSHRLMNATHRBFDPS
SCHEMBL5892589 0.87 TSHR (0.40) TSHRLMNATHRBFDPSESR1
SCHEMBL10930115 0.87 TSHR (0.40) TSHRLMNATHRBFDPSESR1
SCHEMBL208096 0.87 TSHR (0.40) TSHRLMNATHRBFDPSESR1
SCHEMBL16287226 0.87 TSHR (0.33) TSHRFDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101384635-B Polyols based on modified amino resins, their preparation and use BASF COATINGS AG 2011-08-17 CN claimed
US-9745321-B2 Fused pyrimidine compound, intermediate, preparation method therefor, and composition and application thereof SHANGHAI YINGLI PHARMACEUTICAL CO., LTD (CN) 2017-08-29 US disclosed
EP-2078003-B1 ANILINOPIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF MERCK SHARP & DOHME (US) 2017-03-08 EP disclosed
CN-106459345-A Fast drying, elastic energy, scratch resistant and stable coating compounds 巴斯夫欧洲公司 2017-02-22 CN disclosed
CN-101679230-B Mercaptan mixture LANXESS DEUTSCHLAND GMBH 2015-05-13 CN disclosed
CN-101679230-A Mercaptan mixture LANXESS DEUTSCHLAND GMBH 2010-03-24 CN disclosed
CN-101374594-A Powder coating suspensions (powder slurries) and powder coatings, process for producing them and their use BASF COATINGS AG (DE) 2009-02-25 CN disclosed
CN-101155769-A Production of (co)surfactants by reacting polyols with olefins BASF AG (DE) 2008-04-02 CN disclosed
EP-1190004-B1 COATING MATERIAL THAT CAN BE CURED THERMALLY OR BY ACTINIC RADIATION, AND ITS USE BASF COATINGS AG (DE) 2003-07-30 EP disclosed
EP-1190004-A1 COATING MATERIAL THAT CAN BE CURED THERMALLY OR BY ACTINIC RADIATION, AND ITS USE BASF Coatings AG (DE) 2002-03-27 EP disclosed
EP-1159356-A1 AQUEOUS ACRYLIC HOUSE PAINT WITH A BRANCHED POLYOL ADDITIVE BASF Coatings AG (DE) 2001-12-05 EP disclosed
WO-2000073395-A1 COATING MATERIAL THAT CAN BE CURED THERMALLY OR BY ACTINIC RADIATION, AND ITS USE BASF COATINGS AG (DE) 2000-12-07 WO disclosed
WO-2000032703-A1 AQUEOUS ACRYLIC HOUSE PAINT WITH A BRANCHED POLYOL ADDITIVE BASF COATINGS AG (DE) 2000-06-08 WO disclosed
EP-0127948-B1 SILICONE FOAM-SUPPRESSANT COMPOSITIONS DOW CORNING CORPORATION (US) 1987-05-06 EP disclosed
US-4486336-A BLEND OF HIGH AND LOW VISCOSITY POLYSILOXANES WITH AMORPHOUS SILICA DOW CORNING CORPORATION (US) 1984-12-04 US disclosed
US-3959154-A Method and composition for retarding the evaporation of ammonia and amines COX ROBERT POWERS 1976-05-25 US disclosed