SCHEMBL71774

SCHEMBL71774

O=COc1c[nH]c2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.54
CYP2A6 P11509 1/20 0.53
IMPDH2 P12268 1/20 0.53
PBRM1 Q86U86 1/20 0.46
GPR84 Q9NQS5 2/20 0.44
ATM Q13315 2/20 0.44
MAPT P10636 3/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
CYP3A4 P08684 2/20 0.42
AHR P35869 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ALDH1A1 P00352 4/20 0.42
KDM4E B2RXH2 3/20 0.42
HPGD P15428 3/20 0.42
HSD17B10 Q99714 2/20 0.42
HTR1A P08908 1/20 0.42
HTR2A P28223 1/20 0.42
HTR2C P28335 1/20 0.42
HTR2B P41595 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29131483 0.96 SLC22A6 (0.51) SLC22A6CYP2A6IMPDH2PBRM1GPR84
Thiophene SCHEMBL28969160 0.90 SLC22A6 (0.46) SLC22A6CYP2A6IMPDH2PBRM1GPR84
SCHEMBL1198963 0.81 SLC22A6 (0.54) SLC22A6CYP2A6IMPDH2PBRM1GPR84
SCHEMBL27596049 0.79 NR4A2 (0.51) CYP2A6IMPDH2NR4A2PIM1CDK4
SCHEMBL27614758 0.79 IMPDH2 (0.48) SLC22A6IMPDH2NR4A2CDK4CCND1
SCHEMBL3538344 0.77 SLC22A6 (0.58) SLC22A6CYP2A6IMPDH2PBRM1GPR84
SCHEMBL6535531 0.77 SLC22A6 (0.58) SLC22A6CYP2A6IMPDH2PBRM1GPR84
SCHEMBL2000370 0.77 SLC22A6 (0.54) SLC22A6CYP2A6IMPDH2PBRM1GPR84
SCHEMBL6989104 0.77 MEN1 (0.50) SLC22A6PBRM1GPR84ATMMAPT
SCHEMBL27904105 0.77 SLC22A6 (0.50) SLC22A6CYP2A6IMPDH2PBRM1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 858 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036585-A Synthesis method of indole carboxylic acid compound 北京化工大学 2026-05-15 CN claimed
EP-4607278-A1 CHEMICALLY-AMPLIFIED POSITIVE PHOTORESIST COMPOSITION FOR PATTERN PROFILE IMPROVEMENT AND ETCH RESISTANCE ENHANCEMENT Ycchem Co., Ltd. (KR) 2025-08-27 EP claimed
US-20250199405-A1 CHEMICALLY-AMPLIFIED POSITIVE PHOTORESIST COMPOSITION FOR PATTERN PROFILE IMPROVEMENT AND ETCH RESISTANCE ENHANCEMENT YCCHEM CO., LTD. (KR) 2025-06-19 US claimed
CN-119874598-A Indole-3-acetamide derivative and preparation method and application thereof 河北农业大学 2025-04-25 CN claimed
CN-119822483-A Method for degrading perfluorinated compounds in sludge 广东工业大学 2025-04-15 CN claimed
CN-115920673-B High-flux aromatic polyamide reverse osmosis membrane and preparation method thereof 万华化学集团股份有限公司 2025-02-18 CN claimed
EP-4406930-A1 ISOTOPE-LABELLED INDOLE CARBOXYLIC ACID COMPOUND, MIXTURES AND ANALYTICAL METHOD THEREWITH JEOL Ltd. (JP) 2024-07-31 EP claimed
WO-2024085293-A1 CHEMICALLY-AMPLIFIED POSITIVE PHOTORESIST COMPOSITION FOR PATTERN PROFILE IMPROVEMENT AND ETCH RESISTANCE ENHANCEMENT 영창케미칼 주식회사 2024-04-25 WO claimed
US-20240125786-A1 Indole Carboxylic Acid Compound, Indole Carboxylic Acid Compound Mixture, and Analytical Method JEOL LTD. (JP) 2024-04-18 US claimed
CN-113644200-B Organic solar cell based on solid-liquid mixed additive and preparation method thereof 电子科技大学 2024-03-22 CN claimed
EP-0621788-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1994-11-02 EP claimed
US-5272154-A 3,7 substituted indole and indazole compounds and pharmaceutical compositions containing them SANDOZ LTD. (CH) 1993-12-21 US claimed
WO-1993013789-A1 HEMOREGULATORY PEPTIDES SMITHKLINE BEECHAM CORPORATION (US) 1993-07-22 WO claimed
EP-0386628-B1 METHOD FOR THE PREPARATION OF INDOLCARBOXYLIC ACID DERIVATIVES Kali-Chemie Pharma GmbH (DE) 1993-06-23 EP claimed
CN-1068581-A Indigo purification process BASF AG (DE) 1993-02-03 CN claimed
EP-0519971-A1 NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS WHICH CAN BE FORMED FROM 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO-(1,2-a)-PYRIMIDINE. EEC PHARMA SA (FR) 1992-12-30 EP claimed
EP-0464604-A2 1-Indolylalkyl-4-(alkoxy-pyrimidinyl)piperazines Bristol-Myers Squibb Company (US) 1992-01-08 EP claimed
WO-1991013886-A1 NOVEL PHARMACEUTICALLY ACTIVE COMPOUNDS WHICH CAN BE FORMED FROM 1,3,4,6,7,8-HEXAHYDRO-2H-PYRIMIDO-(1,2-a)-PYRIMIDINE EEC-PHARMA S.A. (FR) 1991-09-19 WO claimed
US-4965369-A Method for preparing indole carboxylic acid derivatives KALI-CHEMIE PHARMA GMBH (DE) 1990-10-23 US claimed
EP-0024852-B1 2,3-DIHYDRO-1H-INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES AND THEIR PREPARATION AMERICAN HOME PRODUCTS CORPORATION (US) 1986-09-03 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240125786-A1 Indole Carboxylic Acid Compound, Indole Carboxylic Acid Compound Mixture, and Analytical Method DRD5, H1-5, H1-0 SLC22A6 884/4885CYP2A6 281/4885IMPDH2 154/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.